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NCT04658693 · ClinicalTrials.gov registry record · NA

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

A NA study of Diabetic Peripheral Neuropathy and Lower Extremity Amputee, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT04658693 is a NA study of Diabetic Peripheral Neuropathy and Lower Extremity Amputee that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 15 participants, below the 128-participant average among 17 other Diabetic Peripheral Neuropathy trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04658693, a NA study of Diabetic Peripheral Neuropathy and Lower Extremity Amputee, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the effectiveness of providing sensation of the missing limb to individuals with above and below the knee limb loss. The investigators will implanted stimulating electrodes to send small electrical currents to the remaining nerves. These small electrical currents cause the nerves to generate signals that are then transferred to your brain similar to how the information about your foot and lower limb used to be transferred to the brain prior to your limb loss. Additionally, there is the option to have muscle recording electrodes implanted within the muscles of the lower limb with the goal to develop a motor controller that would allow the user to have intuitive control of a robotic prosthetic leg.

Interventions

  • DEVICE Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode

Study Locations (1)

Ohio

  • Louis Stokes VA Medical Center, Cleveland, OH - Cleveland

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2021-03-02
Est. Completion 2027-09-02
Phase NA

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT04658693

The ClinicalTrials.gov registry entry for NCT04658693 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 128-participant average among 17 other Diabetic Peripheral Neuropathy trials with a reported enrollment target (88% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Diabetic Peripheral Neuropathy appearing as the primary indexed condition, and to 1 intervention - of which Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode is the first listed.

NCT04658693 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT04658693 about?

NCT04658693 is a clinical study titled "Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy". The purpose of this study is to evaluate the effectiveness of providing sensation of the missing limb to individuals with above and below the knee limb loss. The investigators will implanted stimulating electrodes to send small electrical currents to the remaining nerves. These small electrical curr...

What is the current status of trial NCT04658693?

This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2021-03-02. Estimated completion is 2027-09-02.

What conditions does trial NCT04658693 study?

This clinical trial studies the following conditions: Diabetic Peripheral Neuropathy, Lower Extremity Amputee.

What interventions are being tested in trial NCT04658693?

The interventions under investigation include: Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode (DEVICE).

Who is sponsoring clinical trial NCT04658693?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04658693 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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