Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06312748 · ClinicalTrials.gov registry record · Phase 1
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
A Phase 1 study of Inflammation and Heart Failure With Preserved Ejection Fraction, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT06312748 is a Phase 1 study of Inflammation and Heart Failure With Preserved Ejection Fraction that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 90 participants, below the 287-participant average among 132 other Inflammation trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06312748, a Phase 1 study of Inflammation and Heart Failure With Preserved Ejection Fraction, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
This project will evaluate the impact of L-Citrulline, tetrahydrobiopterin (BH4), and atorvastatin administration on physical capacity and vascular function in Veterans with heart failure with preserved ejection fraction (HFpEF).
Conditions Studied
Interventions
- DRUG Atorvastatin
- DRUG L-Citrulline
- DRUG Placebo for L-Citrulline
- DRUG BH4
- DRUG Placebo for BH4
Study Locations (1)
Utah
- VA Salt Lake City Health Care System, Salt Lake City, UT - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2021-05-19 |
| Est. Completion | 2030-09-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06312748
The ClinicalTrials.gov registry entry for NCT06312748 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 287-participant average among 132 other Inflammation trials with a reported enrollment target (69% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Inflammation appearing as the primary indexed condition, and to 5 interventions - of which Atorvastatin is the first listed.
NCT06312748 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.
Frequently Asked Questions
What is clinical trial NCT06312748 about?
NCT06312748 is a clinical study titled "Novel Approaches for Improving Vascular Function in Veterans With HFpEF". This project will evaluate the impact of L-Citrulline, tetrahydrobiopterin (BH4), and atorvastatin administration on physical capacity and vascular function in Veterans with heart failure with preserved ejection fraction (HFpEF).
What is the current status of trial NCT06312748?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 2021-05-19. Estimated completion is 2030-09-30.
What conditions does trial NCT06312748 study?
This clinical trial studies the following conditions: Inflammation, Heart Failure With Preserved Ejection Fraction.
What interventions are being tested in trial NCT06312748?
The interventions under investigation include: Atorvastatin (DRUG), L-Citrulline (DRUG), Placebo for L-Citrulline (DRUG), BH4 (DRUG), Placebo for BH4 (DRUG).
Who is sponsoring clinical trial NCT06312748?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06312748 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Inflammation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
RECRUITING · Phase 1
-
Salt-Sensitivity and Immunity Cell Activation
ACTIVE NOT RECRUITING · Phase 1
-
Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot Study
COMPLETED · Phase 1
-
Flaxseed Modulates Inflammation and Oxidative Stress in CF
COMPLETED · Phase 1
-
Effect of Statin Therapy on C-reactive Protein Levels in Patients With Chronic Obstructive Lung Disease (COPD)
COMPLETED · Phase 1
-
Ketone Ester And Salt (KEAS) in Older Adults
RECRUITING · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.