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NCT03836950 · ClinicalTrials.gov registry record · Phase 1

rTMS to Improve Cognition in Parkinson's

A Phase 1 study of Mild Cognitive Impairment and Parkinson's Disease, sponsored by VA Office of Research and Development.

Recruiting
Registry status
Phase 1
Development phase
56
Enrollment target
2
Study locations

NCT03836950: Recruiting Phase 1 study of Mild Cognitive Impairment and Parkinson's Disease, sponsored by VA Office of Research and Development.

NCT03836950 is a Phase 1 study of Mild Cognitive Impairment and Parkinson's Disease that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 56 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03836950, a Phase 1 study of Mild Cognitive Impairment and Parkinson's Disease, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
Phase 1
Development phase
56 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS), for Veterans with Parkinson's disease or atypical parkinsonism and mild impairments in their thinking. The hypothesis is that rTMS can improve thinking for people with Parkinson's disease or atypical parkinsonism who are experiencing mild problems with their thinking ability.

Primary Outcome

The NIH-EXAMINER has an established 3-factor model defined by (1) cognitive control, (2) working memory (3) fluency. A confirmatory factor analysis indicates these 3-factors load on to 1-factor: executive composite score. Seven tests in the NIH-EXAMINER will be used to compute the composite score

Interventions

  • DEVICE MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)

Study Locations (2)

Illinois

  • Jesse Brown VA Medical Center, Chicago, IL - Chicago
  • Edward Hines Jr. VA Hospital, Hines, IL - Hines

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2020-04-01
Est. Completion 2027-03-30
Phase Phase 1
VA Office of Research and Development

1,668 total trials

What NCT03836950 shows while recruiting

NCT03836950 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (96% lower).

The record links to 2 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark) is the first listed.

NCT03836950 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT03836950 about?

NCT03836950 is a clinical study titled "rTMS to Improve Cognition in Parkinson's". The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS), for Veterans with Parkinson's disease or atypical parkinsonism and mild impairments in their thinking. The hypothesis is...

What is the current status of trial NCT03836950?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2020-04-01. Estimated completion is 2027-03-30.

What conditions does trial NCT03836950 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment, Parkinson's Disease.

What interventions are being tested in trial NCT03836950?

The interventions under investigation include: MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark) (DEVICE).

Who is sponsoring clinical trial NCT03836950?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03836950 being conducted?

This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Mild Cognitive Impairment

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03836950's enrollment target sits among peer trials

56 135th of 205 higher than 71 of 205 other Mild Cognitive Impairment trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03836950, the US trial registry maintained by the National Library of Medicine. NCT03836950 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.