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NCT04877444 · ClinicalTrials.gov registry record · Early Phase 1
Exercise Primed Stroke Rehabilitation
A Early Phase 1 study of Stroke, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT04877444: Recruiting Early Phase 1 study of Stroke, sponsored by VA Office of Research and Development.
NCT04877444 is a Early Phase 1 study of Stroke that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 40 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04877444, a Early Phase 1 study of Stroke, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Stroke is a leading cause of disability in the U.S. and many Veteran stroke survivors live with severe disability. Despite recent advances in rehabilitation treatments many stroke survivors have persistent physical and mental difficulties such as reduced physical and cognitive function and depression. Developing innovative treatments that address these problems is necessary to improve long-term outcomes for stroke survivors. Aerobic exercise (AEx) can improve physical and cognitive function, and reduce depression. Additionally, AEx may enhance physical rehabilitation by making the brain more receptive to, and consequently improving the response to an intervention. Therefore, combining AEx with physical rehabilitation has the potential to improve multiple aspects of stroke recovery. This study will examine the effect of combining AEx with physical rehabilitation on physical and mental function in stroke survivors. By gaining a better understanding of the effects of this combined intervention the investigators aim to advance the rehabilitative care of Veteran stroke survivors.
Primary Outcome
The FMA-UE is a 33-item measure of UE impairment; however, the 3 items testing reflex response will not be administered because they do not measure a voluntary movement construct. Each item will be scored on a 3-point rating scale (0=unable, 1=partial 2=near normal performance), item ratings will be summed and reported out of 60 points so that larger numbers indicate greater UE motor ability.
Conditions Studied
Interventions
- DEVICE Duck Duck Punch
- BEHAVIORAL Aerobic exercise
- BEHAVIORAL Lower extremity stretching
Study Locations (1)
South Carolina
- Ralph H. Johnson VA Medical Center, Charleston, SC - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2027-01-31 |
| Phase | Early Phase 1 |
What NCT04877444 shows while recruiting
NCT04877444 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 3 interventions - of which Duck Duck Punch is the first listed.
NCT04877444 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT04877444 about?
NCT04877444 is a clinical study titled "Exercise Primed Stroke Rehabilitation". Stroke is a leading cause of disability in the U.S. and many Veteran stroke survivors live with severe disability. Despite recent advances in rehabilitation treatments many stroke survivors have persistent physical and mental difficulties such as reduced physical and cognitive function and depressio...
What is the current status of trial NCT04877444?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 40 participants. The study started on 2021-07-01. Estimated completion is 2027-01-31.
What conditions does trial NCT04877444 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT04877444?
The interventions under investigation include: Duck Duck Punch (DEVICE), Aerobic exercise (BEHAVIORAL), Lower extremity stretching (BEHAVIORAL).
Who is sponsoring clinical trial NCT04877444?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04877444 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04877444's enrollment target sits among peer trials
40 262nd of 454 higher than 181 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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