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NCT04199780 · ClinicalTrials.gov registry record · NA
Effects of tDCS Combined With CBI on Postsurgical Pain
A NA study of Total Knee Arthroplasty (Postoperative Pain) and Total Hip Arthroplasty (Postoperative Pain), sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 132
- Enrollment target
- 1
- Study location
NCT04199780: Recruiting NA study of Total Knee Arthroplasty (Postoperative Pain) and Total Hip Arthroplasty (Postoperative Pain), sponsored by VA Office of Research and Development.
NCT04199780 is a NA study of Total Knee Arthroplasty (Postoperative Pain) and Total Hip Arthroplasty (Postoperative Pain) that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 132 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04199780, a NA study of Total Knee Arthroplasty (Postoperative Pain) and Total Hip Arthroplasty (Postoperative Pain), is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 132 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether a new medical technology can help reduce post-operative total knee or hip pain when combined with a Cognitive-Behavioral intervention (CBI). This new medical technology, is called transcranial direct current stimulation (tDCS), it uses a very small amount of electricity to temporarily stimulate specific areas of the brain thought to be involved in pain reduction. The electrical current passes through the skin, scalp, hair, and skull and requires no additional medication, sedation, or needles. This study will investigate the effects of tDCS, the Cognitive-Behavioral (CB) intervention and their combination on pain among veterans following total knee arthroplasty (TKA) or total hip arthroplasty (THA). The Veteran may benefit in the form of decreased pain and opioid requirements following knee or hip replacement surgery. However, benefit is only likely if Veterans are randomized to one of the 3 (out of 4) groups. This study hopes to determine the effects of these interventions and combined effect on post-operative pain, opioid use and functioning during the 48-hour post-operative period following a total knee or hip replacement.
Primary Outcome
Patient controlled analgesic medication usage (the morphine equivalent dose (MED); milligrams (mg) of morphine) during the acute 48-hour post-operative period following total knee arthroplasty (TKA) or total hip arthroplasty (THA).
Conditions Studied
Interventions
- DEVICE Transcranial Direct Current Stimulation
- BEHAVIORAL Cognitive-Behavioral (CB) intervention
Study Locations (1)
South Carolina
- Ralph H. Johnson VA Medical Center, Charleston, SC - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2021-01-11 |
| Est. Completion | 2026-07-31 |
| Phase | NA |
What NCT04199780 shows while recruiting
NCT04199780 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Total Knee Arthroplasty (Postoperative Pain) appearing as the primary indexed condition, and to 2 interventions - of which Transcranial Direct Current Stimulation is the first listed.
NCT04199780 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT04199780 about?
NCT04199780 is a clinical study titled "Effects of tDCS Combined With CBI on Postsurgical Pain". The purpose of this study is to determine whether a new medical technology can help reduce post-operative total knee or hip pain when combined with a Cognitive-Behavioral intervention (CBI). This new medical technology, is called transcranial direct current stimulation (tDCS), it uses a very small ...
What is the current status of trial NCT04199780?
This trial is currently recruiting. It is a NA study. The enrollment target is 132 participants. The study started on 2021-01-11. Estimated completion is 2026-07-31.
What conditions does trial NCT04199780 study?
This clinical trial studies the following conditions: Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain).
What interventions are being tested in trial NCT04199780?
The interventions under investigation include: Transcranial Direct Current Stimulation (DEVICE), Cognitive-Behavioral (CB) intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT04199780?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04199780 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04199780's enrollment target sits among peer trials
132 729th of 2000 higher than 1,270 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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