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NCT05699538 · ClinicalTrials.gov registry record · NA
Fatigability in Long COVID-19
A NA study of Long COVID, sponsored by VA Office of Research and Development.
- Active
- Registry status
- NA
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT05699538: Active NA study of Long COVID, sponsored by VA Office of Research and Development.
NCT05699538 is a NA study of Long COVID that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 21 participants, below the 2,188-participant average among 50 other Long COVID trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05699538, a NA study of Long COVID, is active but no longer recruiting, sponsored by VA Office of Research and Development.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall goal of this project is to advance the understanding of underlying mechanisms impacting performance fatigability and perceived fatigability in Veterans with post-COVID-19 fatigue and explore the safety and feasibility of a home-based "minimal-dose" resistance exercise program in this population. The central hypothesis is that declines in force capacity, skeletal muscle oxygen extraction, and affective responses to physical activity offer potential mechanisms through which fatigability is increased in Veterans with post-COVID-19 fatigue. Moreover, home-based resistance exercise delivered remotely may provide a safe and feasibility treatment option for targeting neuromuscular and neurobehavioral factors influencing fatigability severity in this population.
Primary Outcome
Performance fatigability will be assessed as change in maximal voluntary isometric contraction (MVIC) torque of the dominant leg. Change in MVIC torque from the initial MVIC contraction to the last MVIC contraction will be used to determine the Performance Fatigability index.
Conditions Studied
Interventions
- BEHAVIORAL Minimal-Dose Home-Based Resistance Exercise
Study Locations (1)
District of Columbia
- Washington DC VA Medical Center, Washington, DC - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2023-07-31 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What the registry record for NCT05699538 still lists
NCT05699538 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 2,188-participant average among 50 other Long COVID trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Long COVID appearing as the primary indexed condition, and to 1 intervention - of which Minimal-Dose Home-Based Resistance Exercise is the first listed.
NCT05699538 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT05699538 about?
NCT05699538 is a clinical study titled "Fatigability in Long COVID-19". The overall goal of this project is to advance the understanding of underlying mechanisms impacting performance fatigability and perceived fatigability in Veterans with post-COVID-19 fatigue and explore the safety and feasibility of a home-based "minimal-dose" resistance exercise program in this pop...
What is the current status of trial NCT05699538?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 21 participants. The study started on 2023-07-31. Estimated completion is 2026-03-31.
What conditions does trial NCT05699538 study?
This clinical trial studies the following conditions: Long COVID.
What interventions are being tested in trial NCT05699538?
The interventions under investigation include: Minimal-Dose Home-Based Resistance Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT05699538?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05699538 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Long COVID
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05699538's enrollment target sits among peer trials
21 45th of 50 higher than 5 of 50 other Long COVID trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Long COVID trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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