Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05674617 · ClinicalTrials.gov registry record · NA
PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes
A NA study of Stress Disorders, Post-Traumatic; Mental Disorders, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT05674617: Recruiting NA study of Stress Disorders, Post-Traumatic; Mental Disorders, sponsored by VA Office of Research and Development.
NCT05674617 is a NA study of Stress Disorders, Post-Traumatic; Mental Disorders that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 48 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05674617, a NA study of Stress Disorders, Post-Traumatic; Mental Disorders, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
PTSD is common among Veterans with serious mental illness (SMI). Co-occurring PTSD and SMI lead to poorer mental health and physical functioning than either diagnosis alone. Despite known high prevalence rates of PTSD in SMI populations as well as disparities in prevalence and treatment use for Black, Indigenous, and other people of color (BIPOC), little research has been done to: a) evaluate leading treatments for PTSD in individuals with SMI, and b) develop culturally responsive methods to integrate with PTSD treatments for SMI Veterans. This study aims to address research and clinical gaps by: a) testing the feasibility and acceptability of Written Exposure Therapy (WET), a VA evidence-based psychotherapy for PTSD in Veterans with SMI, and b) incorporating culturally responsive assessment methods. Results from this study will inform whether WET and culturally responsive assessment are feasible to implement, acceptable to Veterans with SMI, and worth examining in standard or optimized form in a larger clinical trial.
Primary Outcome
As a measure of feasibility, the investigators will evaluate recruitment and suitability of eligibility criteria by calculating number eligible participants (e.g., those that passed screening) divided by number potential participants that were approached for recruitment.
Conditions Studied
Interventions
- BEHAVIORAL Written Exposure Therapy
- BEHAVIORAL PTSD Education
Study Locations (1)
Maryland
- Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2023-12-01 |
| Est. Completion | 2028-03-31 |
| Phase | NA |
What NCT05674617 shows while recruiting
NCT05674617 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Stress Disorders, Post-Traumatic; Mental Disorders appearing as the primary indexed condition, and to 2 interventions - of which Written Exposure Therapy is the first listed.
NCT05674617 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05674617 about?
NCT05674617 is a clinical study titled "PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes". PTSD is common among Veterans with serious mental illness (SMI). Co-occurring PTSD and SMI lead to poorer mental health and physical functioning than either diagnosis alone. Despite known high prevalence rates of PTSD in SMI populations as well as disparities in prevalence and treatment use for Blac...
What is the current status of trial NCT05674617?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2023-12-01. Estimated completion is 2028-03-31.
What conditions does trial NCT05674617 study?
This clinical trial studies the following conditions: Stress Disorders, Post-Traumatic; Mental Disorders.
What interventions are being tested in trial NCT05674617?
The interventions under investigation include: Written Exposure Therapy (BEHAVIORAL), PTSD Education (BEHAVIORAL).
Who is sponsoring clinical trial NCT05674617?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05674617 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05674617's enrollment target sits among peer trials
48 1381st of 2000 higher than 601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01765777 · 48 participants · NA
Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients With Chronic Lower Back Pain
- NCT03073343 · 48 participants · NA
A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine
- NCT03431064 · 48 participants
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
- NCT03514602 · 48 participants · NA
Maternal Smoking Cessation and Pediatric Obesity Prevention
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI