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NCT05811312 · ClinicalTrials.gov registry record
Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study
A clinical trial of Neuropathic Pain, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT05811312: Recruiting study of Neuropathic Pain, sponsored by VA Office of Research and Development.
NCT05811312 is a study of Neuropathic Pain that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 40 participants, below the 100-participant average among 35 other Neuropathic Pain trials with a reported enrollment target (60% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05811312, a study of Neuropathic Pain, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The investigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.
Primary Outcome
Resting state functional connectivity will be evaluated with fNIRS and EEG. The investigators will model "response to SCS" with changes in resting state functional connectivity between five bilateral cortical regions. These regions are the medial prefrontal cortex (mPF), dorsolateral prefrontal cortex (DLPFC), primary motor cortex (M1), primary sensory cortex (S1), and posterior parietal cortex (PPC). Brain connectivity will be evaluated with fNIRS and EEG. Prefrontal medial cortex and posterior
Conditions Studied
Study Locations (1)
Ohio
- Louis Stokes VA Medical Center, Cleveland, OH - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-07-01 |
| Est. Completion | 2026-06-30 |
What NCT05811312 shows while recruiting
NCT05811312 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 100-participant average among 35 other Neuropathic Pain trials with a reported enrollment target (60% lower).
The record links to 1 condition, with Neuropathic Pain appearing as the primary indexed condition, and to 0 interventions.
NCT05811312 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05811312 about?
NCT05811312 is a clinical study titled "Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study". This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The investi...
What is the current status of trial NCT05811312?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2023-07-01. Estimated completion is 2026-06-30.
What conditions does trial NCT05811312 study?
This clinical trial studies the following conditions: Neuropathic Pain.
Who is sponsoring clinical trial NCT05811312?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05811312 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05811312's enrollment target sits among peer trials
40 17th of 35 higher than 19 of 35 other Neuropathic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Neuropathic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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