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NCT05789329 · ClinicalTrials.gov registry record · NA
Non-Inferiority Trial of TrIGR for PTSD
A NA study of PTSD, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 158
- Enrollment target
- 2
- Study locations
NCT05789329 is a NA study of PTSD that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 158 participants, below the 301-participant average among 154 other PTSD trials with a reported enrollment target (48% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT05789329, a NA study of PTSD, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 158 participants
- Enrollment target
- 2
- Study locations
Study Summary
Trauma-related guilt is common and impairing among trauma survivors, particularly among Veterans with posttraumatic stress disorder (PTSD). The investigators' work shows that a brief treatment targeting trauma-related guilt, Trauma Informed Guilt Reduction Therapy (TrIGR), can reduce guilt and PTSD and depression symptoms. Whether TrIGR is no less effective than longer, more resource heavy PTSD treatments disseminated by by VA, like cognitive processing therapy (CPT), is the next critical question that this study will seek to answer. 158 Veterans across two VA sites will be randomized to TrIGR or CPT to evaluate changes in PTSD, depression, guilt and shame symptoms across the two treatments.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Processing Therapy
- BEHAVIORAL Trauma Informed Guilt Reduction Therapy
Study Locations (2)
California
- VA San Diego Healthcare System, San Diego, CA - San Diego
Florida
- James A. Haley Veterans' Hospital, Tampa, FL - Tampa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 158 participants |
| Start Date | 2023-06-01 |
| Est. Completion | 2027-09-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05789329
The ClinicalTrials.gov registry entry for NCT05789329 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 158 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 301-participant average among 154 other PTSD trials with a reported enrollment target (48% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with PTSD appearing as the primary indexed condition, and to 2 interventions - of which Cognitive Processing Therapy is the first listed.
NCT05789329 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Florida.
Frequently Asked Questions
What is clinical trial NCT05789329 about?
NCT05789329 is a clinical study titled "Non-Inferiority Trial of TrIGR for PTSD". Trauma-related guilt is common and impairing among trauma survivors, particularly among Veterans with posttraumatic stress disorder (PTSD). The investigators' work shows that a brief treatment targeting trauma-related guilt, Trauma Informed Guilt Reduction Therapy (TrIGR), can reduce guilt and PTSD ...
What is the current status of trial NCT05789329?
This trial is currently recruiting. It is a NA study. The enrollment target is 158 participants. The study started on 2023-06-01. Estimated completion is 2027-09-30.
What conditions does trial NCT05789329 study?
This clinical trial studies the following conditions: PTSD.
What interventions are being tested in trial NCT05789329?
The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL), Trauma Informed Guilt Reduction Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT05789329?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05789329 being conducted?
This trial has 2 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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