Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING NA

High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans

NCT05625204 · View on ClinicalTrials.gov ↗

Study Summary

Frailty is defined as a greater susceptibility to stressors resulting from age-related impairments in adaptive biological systems. Frailty leads to poorer physical performance and functional capacity and higher risk of adverse outcomes including falls, hospitalization, and mortality. Resilience, defined as the capacity to recover from disruptions to homeostasis, is critical to successful aging because it precedes frailty and enhances adults' ability to maintain optimal health and function well into older age. Evidence- based therapies to help older adults enhance resilience are limited and the biological underpinnings contributing to improved resilience have not yet been fully characterized. To address this important need, the investigators will conduct a clinical trial to examine the benefits of center- and home-based high intensity interval training (HIIT) on functional capacity, frailty, and resilience, and also to identify novel biomarkers of resilience in older Veterans.

Conditions Studied

Interventions

  • BEHAVIORAL Center based attention (stretching only) control
  • BEHAVIORAL Center based HIIT
  • BEHAVIORAL Home based HIIT

Study Locations (2)

Missouri

  • Kansas City VA Medical Center, Kansas City, MO — Kansas City
  • Kansas City VA Medical Center, Kansas City, MO — Kansas City

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2024-01-29
Est. Completion 2027-09-30
Phase NA

Sponsor

VA Office of Research and Development

1,863 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05625204

The ClinicalTrials.gov registry entry for NCT05625204 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,863 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Frailty appearing as the primary indexed condition, and to 3 interventions — of which Center based attention (stretching only) control is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05625204 reports 2 study locations spanning 1 distinct geographic area — top geographies include Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05625204 about?

NCT05625204 is a clinical study titled "High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans". Frailty is defined as a greater susceptibility to stressors resulting from age-related impairments in adaptive biological systems. Frailty leads to poorer physical performance and functional capacity and higher risk of adverse outcomes including falls, hospitalization, and mortality. Resilience, def...

What is the current status of trial NCT05625204?

This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2024-01-29. Estimated completion is 2027-09-30.

What conditions does trial NCT05625204 study?

This clinical trial studies the following conditions: Frailty. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05625204?

The interventions under investigation include: Center based attention (stretching only) control (BEHAVIORAL), Center based HIIT (BEHAVIORAL), Home based HIIT (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05625204?

This trial is sponsored by VA Office of Research and Development, which has 1,863 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05625204 being conducted?

This trial has 2 study locations across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial