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NCT05625204 · ClinicalTrials.gov registry record · NA
High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans
A NA study of Frailty, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 2
- Study locations
NCT05625204: Recruiting NA study of Frailty, sponsored by VA Office of Research and Development.
NCT05625204 is a NA study of Frailty that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 200 participants, below the 1,502-participant average among 48 other Frailty trials with a reported enrollment target (87% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05625204, a NA study of Frailty, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 2
- Study locations
Study Summary
Frailty is defined as a greater susceptibility to stressors resulting from age-related impairments in adaptive biological systems. Frailty leads to poorer physical performance and functional capacity and higher risk of adverse outcomes including falls, hospitalization, and mortality. Resilience, defined as the capacity to recover from disruptions to homeostasis, is critical to successful aging because it precedes frailty and enhances adults' ability to maintain optimal health and function well into older age. Evidence- based therapies to help older adults enhance resilience are limited and the biological underpinnings contributing to improved resilience have not yet been fully characterized. To address this important need, the investigators will conduct a clinical trial to examine the benefits of center- and home-based high intensity interval training (HIIT) on functional capacity, frailty, and resilience, and also to identify novel biomarkers of resilience in older Veterans.
Primary Outcome
Participants are asked to exercise on an upright exercise bike as the resistance increases over time. During the exercise, participants are asked to breath through a mask that is connected to a oxygen and carbon dioxide measuring device. The assessment last for approximately 5-10 minutes and provides data the pertain to an individuals lung capacity, breathing rate, and endurance.
Conditions Studied
Interventions
- BEHAVIORAL Center based attention (stretching only) control
- BEHAVIORAL Center based HIIT
- BEHAVIORAL Home based HIIT
Study Locations (2)
Missouri
- Kansas City VA Medical Center, Kansas City, MO - Kansas City
- Kansas City VA Medical Center, Kansas City, MO - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-01-29 |
| Est. Completion | 2027-09-30 |
| Phase | NA |
What NCT05625204 shows while recruiting
NCT05625204 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,502-participant average among 48 other Frailty trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Frailty appearing as the primary indexed condition, and to 3 interventions - of which Center based attention (stretching only) control is the first listed.
NCT05625204 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT05625204 about?
NCT05625204 is a clinical study titled "High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans". Frailty is defined as a greater susceptibility to stressors resulting from age-related impairments in adaptive biological systems. Frailty leads to poorer physical performance and functional capacity and higher risk of adverse outcomes including falls, hospitalization, and mortality. Resilience, def...
What is the current status of trial NCT05625204?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2024-01-29. Estimated completion is 2027-09-30.
What conditions does trial NCT05625204 study?
This clinical trial studies the following conditions: Frailty.
What interventions are being tested in trial NCT05625204?
The interventions under investigation include: Center based attention (stretching only) control (BEHAVIORAL), Center based HIIT (BEHAVIORAL), Home based HIIT (BEHAVIORAL).
Who is sponsoring clinical trial NCT05625204?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05625204 being conducted?
This trial has 2 study locations across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Frailty
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05625204's enrollment target sits among peer trials
200 9th of 48 higher than 40 of 48 other Frailty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Frailty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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