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NCT06059872 · ClinicalTrials.gov registry record · NA
Biomarkers of Reaction To HIIT Exercise
A NA study of Stroke and Walking, Difficulty, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 55
- Enrollment target
- 1
- Study location
NCT06059872: Recruiting NA study of Stroke and Walking, Difficulty, sponsored by VA Office of Research and Development.
NCT06059872 is a NA study of Stroke and Walking, Difficulty that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 55 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06059872, a NA study of Stroke and Walking, Difficulty, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 55 participants
- Enrollment target
- 1
- Study location
Study Summary
Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive model that identifies if a Veteran with chronic subcortical stroke will improve their walking speed with HIIT by incorporating blood lactate as an early predictor of exercise response, and inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and regional cerebral blood flow (CBF) as predictors of the brain's potential to respond, while also taking into consideration other factors such as comorbidities, demographics, and fitness levels.
Primary Outcome
To assess short-distance walking speed and gait characteristics.
Conditions Studied
Interventions
- OTHER High Intensity Interval Training (HIIT)
Study Locations (1)
Georgia
- Atlanta VA Medical and Rehab Center, Decatur, GA - Decatur
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2024-01-01 |
| Est. Completion | 2027-12-01 |
| Phase | NA |
What NCT06059872 shows while recruiting
NCT06059872 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 4 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which High Intensity Interval Training (HIIT) is the first listed.
NCT06059872 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT06059872 about?
NCT06059872 is a clinical study titled "Biomarkers of Reaction To HIIT Exercise". Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive...
What is the current status of trial NCT06059872?
This trial is currently recruiting. It is a NA study. The enrollment target is 55 participants. The study started on 2024-01-01. Estimated completion is 2027-12-01.
What conditions does trial NCT06059872 study?
This clinical trial studies the following conditions: Stroke, Walking, Difficulty, Stroke Rehabilitation, Lower Extremity Weakness, Spastic.
What interventions are being tested in trial NCT06059872?
The interventions under investigation include: High Intensity Interval Training (HIIT) (OTHER).
Who is sponsoring clinical trial NCT06059872?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06059872 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06059872's enrollment target sits among peer trials
55 225th of 454 higher than 228 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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