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NCT05994482 · ClinicalTrials.gov registry record
Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
A clinical trial of Colorectal Cancer, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- 130,000
- Enrollment target
- 2
- Study locations
NCT05994482: Recruiting study of Colorectal Cancer, sponsored by VA Office of Research and Development.
NCT05994482 is a study of Colorectal Cancer that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 130,000 participants, above the 1,203-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (10706% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05994482, a study of Colorectal Cancer, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- 130,000 participants
- Enrollment target
- 2
- Study locations
Study Summary
Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended. However, it is unclear whether repeat additional colonoscopy further reduces risk for colorectal cancer. For older adults age 75 and older, the lack of this information is especially important, given that the risks of colonoscopy go up with age. This research will evaluate whether older adults with a prior history of precancerous polyps have higher colorectal cancer risks compared to older adults who had a prior normal colonoscopy, and whether, among those with prior precancerous polyps, repeating a colonoscopy after age 75 is associated with reduced cancer risk. The investigators will synthesize these data and gather perspectives from Veterans and clinical stakeholders to make recommendations on whether older adults with a prior history of polyps should continue or defer colonoscopy after age 75.
Primary Outcome
colorectal cancer
Conditions Studied
Interventions
- OTHER adenoma vs no adenoma
- OTHER colonoscopy vs no colonoscopy
- OTHER survey and expert panel
Study Locations (2)
California
- VA San Diego Healthcare System, San Diego, CA - San Diego
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA - West Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130,000 participants |
| Start Date | 2023-10-01 |
| Est. Completion | 2027-09-30 |
What NCT05994482 shows while recruiting
NCT05994482 is an observational study that tracks outcomes without assigning an intervention. Its 130,000 participants enrollment target places it among the larger protocols in the corpus, above the 1,203-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (10706% higher).
The record links to 1 condition, with Colorectal Cancer appearing as the primary indexed condition, and to 3 interventions - of which adenoma vs no adenoma is the first listed.
NCT05994482 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05994482 about?
NCT05994482 is a clinical study titled "Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study". Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended. However, it is unclear whether repeat additional colonoscopy further re...
What is the current status of trial NCT05994482?
This trial is currently recruiting. The enrollment target is 130,000 participants. The study started on 2023-10-01. Estimated completion is 2027-09-30.
What conditions does trial NCT05994482 study?
This clinical trial studies the following conditions: Colorectal Cancer.
What interventions are being tested in trial NCT05994482?
The interventions under investigation include: adenoma vs no adenoma (OTHER), colonoscopy vs no colonoscopy (OTHER), survey and expert panel (OTHER).
Who is sponsoring clinical trial NCT05994482?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05994482 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05994482's enrollment target sits among peer trials
130,000 1st of 381 higher than 381 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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