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NCT05994482 · ClinicalTrials.gov registry record

Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study

A clinical trial of Colorectal Cancer, sponsored by VA Office of Research and Development.

Recruiting
Registry status
130,000
Enrollment target
2
Study locations

NCT05994482 is a study of Colorectal Cancer that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 130,000 participants, above the 1,159-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (11117% higher). The trial reports 2 study locations across 1 state.

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The verdict

NCT05994482, a study of Colorectal Cancer, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
130,000 participants
Enrollment target
2
Study locations

Study Summary

Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended. However, it is unclear whether repeat additional colonoscopy further reduces risk for colorectal cancer. For older adults age 75 and older, the lack of this information is especially important, given that the risks of colonoscopy go up with age. This research will evaluate whether older adults with a prior history of precancerous polyps have higher colorectal cancer risks compared to older adults who had a prior normal colonoscopy, and whether, among those with prior precancerous polyps, repeating a colonoscopy after age 75 is associated with reduced cancer risk. The investigators will synthesize these data and gather perspectives from Veterans and clinical stakeholders to make recommendations on whether older adults with a prior history of polyps should continue or defer colonoscopy after age 75.

Conditions Studied

Interventions

  • OTHER adenoma vs no adenoma
  • OTHER colonoscopy vs no colonoscopy
  • OTHER survey and expert panel

Study Locations (2)

California

  • VA San Diego Healthcare System, San Diego, CA - San Diego
  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA - West Los Angeles

Trial Details

FieldValue
Enrollment Target 130,000 participants
Start Date 2023-10-01
Est. Completion 2027-09-30

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT05994482

The ClinicalTrials.gov registry entry for NCT05994482 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 130,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,159-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (11117% higher). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Colorectal Cancer appearing as the primary indexed condition, and to 3 interventions - of which adenoma vs no adenoma is the first listed.

NCT05994482 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05994482 about?

NCT05994482 is a clinical study titled "Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study". Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended. However, it is unclear whether repeat additional colonoscopy further re...

What is the current status of trial NCT05994482?

This trial is currently recruiting. The enrollment target is 130,000 participants. The study started on 2023-10-01. Estimated completion is 2027-09-30.

What conditions does trial NCT05994482 study?

This clinical trial studies the following conditions: Colorectal Cancer.

What interventions are being tested in trial NCT05994482?

The interventions under investigation include: adenoma vs no adenoma (OTHER), colonoscopy vs no colonoscopy (OTHER), survey and expert panel (OTHER).

Who is sponsoring clinical trial NCT05994482?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05994482 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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