University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 1 of 16

RECRUITING Phase 1

Breakthrough - T1DM and Chronic Kidney Disease

NCT07592000

RECRUITING Phase 1

Lactulose to Improve Gut Health in Cancer Patients Receiving Immunotherapy

NCT07354100

RECRUITING Phase 2

A Study Evaluating The Combination of Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer

NCT07603856

RECRUITING NA

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

NCT06837220

RECRUITING NA

Spiritual Care Intervention in Adult Patients Diagnosed With Acute Leukemia

NCT07405424

RECRUITING NA

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

NCT06824818

RECRUITING NA

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

NCT06446661

RECRUITING

Geriatric Assessment and Technology Evaluation in Prostate Cancer

NCT06215508

RECRUITING Phase 1

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

NCT07294677

RECRUITING Phase 1

Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty

NCT07672301

RECRUITING NA

Achieving Routine Intervention and Screening for Emotional Health

NCT06887049

RECRUITING Phase 2

Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer

NCT07290621

RECRUITING NA

Effect of Early Parent Education on Children's Sleep

NCT07515534

RECRUITING NA

Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

NCT07126509

RECRUITING

Prospective Assessments Following Immediate Lymphatic Reconstruction

NCT07227467

RECRUITING Early Phase 1

SGLT2i in Kidney Stones

NCT07055282

RECRUITING NA

PSMA PET for Surveillance After Focal Therapy

NCT07115914

RECRUITING NA

STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

NCT06693310

RECRUITING NA

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831

RECRUITING Phase 2

Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer

NCT07065630

RECRUITING NA

Oxalate and Citrate in Humans - Response to Citrate

NCT06944223

RECRUITING

Investigating Periprosthetic Fracture Cultures in Arthroplasty

NCT06952738

RECRUITING Phase 1

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

NCT06912087

RECRUITING Phase 2

Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

NCT04107077

RECRUITING Phase 1

Hypofractionation (Radiation) Trial for Multiple Myeloma

NCT06270888

RECRUITING NA

Investigating Patient Satisfaction With Smart Knee Implants

NCT06968143

RECRUITING Phase 1

The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial

NCT06871111

RECRUITING NA

Auricular Acupressure in Prehabilitation

NCT06516198

RECRUITING Phase 2

Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment

NCT06669572

RECRUITING

FITting Non-invasive Tests in Lynch Syndrome Surveillance

NCT06898996

RECRUITING NA

Tibial IMN Vs. Tibial Micromotion IMN

NCT06976801

RECRUITING Early Phase 1

Drug Effects on Mood and Behavior - Expectancy

NCT07061886

RECRUITING Early Phase 1

Mood Effects of Serotonin Agonists: Depression

NCT07017478

RECRUITING NA

A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy

NCT06382272

RECRUITING NA

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

NCT06785324

RECRUITING Phase 2

Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation

NCT05790213

RECRUITING Phase 2

Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis

NCT06859164

RECRUITING NA

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

NCT06395415

RECRUITING NA

New Strategies to Enhance Smoking Cessation

NCT06751927

RECRUITING

Work2Prevent Plus: Structural Intervention to Promote HIV Care in Black Sexual Minority Men

NCT06894199

RECRUITING Phase 3

Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation

NCT06499857

RECRUITING NA

Does Ethyl Chloride Spray Work?

NCT06651788

RECRUITING Phase 2

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

NCT06635889

RECRUITING NA

Recovery Legal Care Clinical Trial

NCT06618794

RECRUITING NA

Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk

NCT06965686

RECRUITING NA

Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago

NCT07125144

RECRUITING

Dysbiosis & Long COVID

NCT06825819

RECRUITING NA

AYA OMGYES Sexual Health Study

NCT06868121

RECRUITING Phase 2

A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer

NCT05726292

RECRUITING Phase 2

Oxytocin Pharmacokinetics and Pharmacodynamics

NCT05488457

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Chicago pipeline card: 796 registered trials from official public datasets.Report a data error.