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Diabetes Mellitus, Type 1: full-pipeline trial registry
39 of 119 indexed Diabetes Mellitus, Type 1 trials are currently recruiting.
Corpus placement: #105 of 28,707 conditions by registered trial count.
119 US clinical trials · 39 currently recruiting · #105 of 28,707 conditions by registered trial count
Diabetes Mellitus, Type 1: 119 US clinical trials tracked, 39 recruiting.
Diabetes Mellitus, Type 1 is the subject of 119 registered US clinical trials on ClinicalTrials.gov, 39 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 11 of these trials.
Enrollment posture brief
Registry condition diabetes-mellitus-type-1
OPEN 39 | RECR 33% | LATE 31 | EARLY 27 | RANK #105 | SPON 11
Volume-matched condition peers
Nearest open-share peer: Non-alcoholic Fatty Liver Disease (33% recruiting · 58 trials)
Diabetes Mellitus, Type 1 lists 39 open slots (33% of 119 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetes Mellitus, Type 1 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diabetes Mellitus, Type 1 is recruiting below its size-band peers.
39 of 119 indexed trials (32.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diabetes Mellitus, Type 1 trials is spread across many organizations.
Novo Nordisk A/S accounts for 11 of 119 trials (9.2%). 70 distinct sponsors appear on at least one study for this condition label.
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Typical Diabetes Mellitus, Type 1 enrolment sits around 73 participants.
Median target enrolment is 73 among the 119 trials that report a genuine target (sentinel values excluded). 70 of those (58.8%) plan for fewer than 100 participants.
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Diabetes Mellitus, Type 1 research is mostly interventional.
105 interventional and 14 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
119 total, page 1 of 3
TrialNet Pathway to Prevention of T1D
University of South Florida
NCT00097292
The T1D Exchange Registry
T1D Exchange, United States
NCT04629586
Genetics Of Autoimmunity In Type I Diabetes
Medical College of Wisconsin
NCT03648918
Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes
T1D Exchange, United States
NCT06931275
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
Novo Nordisk A/S
NCT07076199
T1D Pregnancy & Me
Jaeb Center for Health Research
NCT06959316
Type 1 Diabetes Recurrence in Pancreas Transplants
University of Miami
NCT01047865
Closed Loop and Education for Hypoglycemia Awareness Restoration
Milton S. Hershey Medical Center
NCT06325202
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Eli Lilly and Company
NCT07222332
Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART
University of North Carolina, Chapel Hill
NCT06405373
National Institute of Diabetes and Digestive Kidney Diseases* Share Plus: Continuous Glucose Monitoring with Data Sharing in Older Adults with Type 1 Diabetes* and Their Care Partners to Improve Time in Range and Reduce Diabetes Distress.
University of Utah
NCT05937321
Food Insecurity Reduction & Strategy Team
Stanford University
NCT06329375
Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes
Massachusetts General Hospital
NCT05180591
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Eli Lilly and Company
NCT07222137
Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes
vTv Therapeutics
NCT06334133
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Alessandro Doria
NCT06217302
Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes
Boston Medical Center
NCT06236607
Diabetes Learning in Virtual Environments Just in Time for Community Reentry
Louise Reagan
NCT05286892
Device Use Reimagined Through Education And Mentorship
University of California, San Francisco
NCT06546930
Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes
University of California, Davis
NCT04428658
Game-based Pediatric Diabetes Education
Carnegie Mellon University
NCT06264258
Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes
University of Colorado, Denver
NCT05819138
Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells
Medical University of South Carolina
NCT04061746
Efficacy and Safety of a Ketogenic Diet in Type 1 Diabetes
Washington University School of Medicine
NCT06503809
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
Vertex Pharmaceuticals Incorporated
NCT04786262
Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes
Boston Children's Hospital
NCT05899166
Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes
Samita Garg
NCT06046833
Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes
Nemours Children's Clinic
NCT05849753
Starting Technology in At Risk Type 1 Diabetes Study
University of California, Los Angeles
NCT06453928
Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery
Jaeb Center for Health Research
NCT06880835
Subcutaneous Pharmacokinetic Evaluation of Monomeric Insulin and Lyumjev in Adults With Type 1 Diabetes
Stanford University
NCT07090824
Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes
City of Hope Medical Center
NCT03746769
Feasibility Study of Extended Wear Insulin Infusion Set Options During Home Use in People With Type 1 Diabetes
Tandem Diabetes Care
NCT07325461
Islet Transplantation in Patients With "Brittle" Type I Diabetes
University of Chicago
NCT01630850
Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes
Creative Medical Technology Holdings
NCT05626712
Regulation of Brain Glucose Metabolism in Type 1 Diabetes
Yale University
NCT05317455
CBTi for the Treatment of Insomnia in Type 1 Diabetes
University of Illinois at Chicago
NCT07091318
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Otsuka Pharmaceutical Factory
NCT06575426
Islet Transplantation in Type 1 Diabetic Kidney Allograft
University of Chicago
NCT01241864
Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec
Diasome Pharmaceuticlas
NCT06238778
Recent-Onset Type 1 Diabetes Extension Study Evaluating the Long-Term Safety of Teplizumab (PROTECT Extension)
Provention Bio, a Sanofi Company
NCT04598893
Using Technology to Address Disparities and Promote Healthcare Equity in Type 1 Diabetes Registry
University of Chicago
NCT06899984
Testing an Integrated Care Model Trial
Emory University
NCT06448429
Diabetes Autoimmunity Withdrawn In New Onset and In Established Patients
Tolerion
NCT03895437
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT05743244
Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus
Maisa N. Feghali, MD
NCT03570632
Recurrent Hypoglycemia in Type 1 Diabetes (Aim 2)
University of Minnesota
NCT04387422
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus
University of Colorado, Denver
NCT03945747
Allogenic Islet Cell Transplantation
University of Chicago
NCT00160732
Type 1 Together: A Peer Mentorship Program to Bolster Use of CGM
Nemours Children's Clinic
NCT06203067
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 14 |
| Phase 3 | 23 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetes Mellitus, Type 1 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetes Mellitus, Type 1 trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetes Mellitus, Type 1 page
119 registered trials, 39 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 39 Diabetes Mellitus, Type 1 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Novo Nordisk A/S sponsors the most Diabetes Mellitus, Type 1 trials on record, review their full trial history before evaluating a specific study. See Novo Nordisk A/S's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus, Type 1 condition card totals 119 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.