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Kidney Stone clinical trials
Every US clinical trial registered for Kidney Stone — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
29 US clinical trials · 15 currently recruiting
The research picture
Kidney Stone has 29 registered US clinical trials, 15 of them open to new participants right now — about 52% of the total.
- 15
- recruiting participants now
- 52%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 10
- top sponsor: University of Alabama at Birmingham
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Access Sheath and Stent Trial
University of Michigan
NCT07297953
High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy
Northwestern University
NCT05006937
ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach
University of Kansas Medical Center
NCT06547632
Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off
Northwestern University
NCT06346483
Oxalate Formation From Ascorbic Acid
University of Alabama at Birmingham
NCT04603898
Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
The Cleveland Clinic
NCT05993546
Gut Oxalate Absorption in Calcium Oxalate Stone Disease
University of Alabama at Birmingham
NCT06331546
Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes
University of Kansas Medical Center
NCT06576661
Oxalate and Citrate
University of Chicago
NCT05334979
Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease
University of Alabama at Birmingham
NCT06210009
O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease
University of Alabama at Birmingham
NCT06330246
Kidney Stone Inflammation
University of Chicago
NCT06436235
NSAIDs Stent Study
Washington University School of Medicine
NCT03638999
GI Oxalate Absorption
University of Chicago
NCT05356000
Oxalate and Citrate in Humans - Response to Citrate
University of Chicago
NCT06944223
A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System
Calyxo
NCT07225933
SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)
SonoMotion
NCT05701098
Dietary Oxalate and Immune Cell Function
University of Alabama at Birmingham
NCT03877276
Reducing Opioid Prescription After Kidney Stone Removal Surgery
Mayo Clinic
NCT05353478
Influence of Obesity on Endogenous Oxalate Synthesis
University of Alabama at Birmingham
NCT03704350
Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers
University of Alabama at Birmingham
NCT04333745
Dietary Oxalate and Innate Immunity in Kidney Stone Disease
University of Alabama at Birmingham
NCT04051346
Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers
University of Alabama at Birmingham
NCT04633811
Potassium Citrate and Crystal Light Lemonade
Northwestern University
NCT05389995
Evaluation of Infection in Obstructing Urolithiasis
University of Texas Southwestern Medical Center
NCT04332861
Perioperative Pregabalin in Ureteroscopy
University of Missouri-Columbia
NCT04122196
MIP Versus PCNL for Kidney Stone Disease
University of California, San Diego
NCT04767919
Assessment of Endogenous Oxalate Synthesis
University of Alabama at Birmingham
NCT05229952
Standard vs Mini-PCNL for the Treatment of Stone Disease
The Cleveland Clinic
NCT04069013
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Kidney Stone Trial Landscape
ClinicalTrials.gov lists 29 US studies indexed under Kidney Stone, and 15 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Kidney Stone shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Kidney Stone is led by University of Alabama at Birmingham with 10 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 29 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Kidney Stone?
PlainTrial tracks 29 US clinical trials for Kidney Stone, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Kidney Stone?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.