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ClinicalTrials.gov 15 recruiting now early-phase tilt

Kidney Stone: early-phase trial registry

15 of 29 indexed Kidney Stone trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #552 of 28,707 conditions by registered trial count.

29 US clinical trials · 15 currently recruiting · #552 of 28,707 conditions by registered trial count

Kidney Stone: 29 US clinical trials tracked, 15 recruiting.

Kidney Stone is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Alabama at Birmingham, running 10 of these trials.

Enrollment posture brief

Registry condition kidney-stone

OPEN 15 | RECR 52% | LATE 0 | EARLY 2 | RANK #552 | SPON 10

Nearest open-share peer: Recurrent Acute Myeloid Leukemia (52% recruiting · 58 trials)

Advanced Breast Cancer62.1%Kidney Stone (this)52%Amyloidosis51.7%Arthritis, Rheumatoid17.2%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Kidney Stone

Kidney Stone lists 15 open slots (52% of 29 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Kidney Stone on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Kidney Stone is recruiting above its size-band peers.

    15 of 29 indexed trials (51.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Kidney Stone research.

    University of Alabama at Birmingham accounts for 10 of 29 trials (34.5%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Most Kidney Stone trials plan to enrol fewer than 100 people.

    Median target enrolment is 75 among the 29 trials that report a genuine target (sentinel values excluded). 20 of those (69%) plan for fewer than 100 participants.

  4. Kidney Stone research is mostly interventional.

    25 interventional and 4 observational studies make up this index (86.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21

Open and recent trials

29 total, page 1 of 1

RECRUITING NA 184 participants

Access Sheath and Stent Trial

University of Michigan

NCT07297953

RECRUITING NA 168 participants

High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy

Northwestern University

NCT05006937

RECRUITING NA 150 participants

ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach

University of Kansas Medical Center

NCT06547632

RECRUITING NA 150 participants

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

Northwestern University

NCT06346483

RECRUITING NA 136 participants

Oxalate Formation From Ascorbic Acid

University of Alabama at Birmingham

NCT04603898

RECRUITING NA 90 participants

Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis

The Cleveland Clinic

NCT05993546

RECRUITING NA 80 participants

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

University of Alabama at Birmingham

NCT06331546

RECRUITING NA 80 participants

Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes

University of Kansas Medical Center

NCT06576661

RECRUITING NA 50 participants

Oxalate and Citrate

University of Chicago

NCT05334979

RECRUITING NA 48 participants

Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease

University of Alabama at Birmingham

NCT06210009

RECRUITING NA 40 participants

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06330246

RECRUITING 40 participants

Kidney Stone Inflammation

University of Chicago

NCT06436235

RECRUITING Early Phase 1 36 participants

NSAIDs Stent Study

Washington University School of Medicine

NCT03638999

RECRUITING NA 30 participants

GI Oxalate Absorption

University of Chicago

NCT05356000

RECRUITING NA 24 participants

Oxalate and Citrate in Humans - Response to Citrate

University of Chicago

NCT06944223

ACTIVE NOT RECRUITING 3,000 participants

A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System

Calyxo

NCT07225933

ACTIVE NOT RECRUITING NA 116 participants

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

SonoMotion

NCT05701098

ACTIVE NOT RECRUITING NA 82 participants

Dietary Oxalate and Immune Cell Function

University of Alabama at Birmingham

NCT03877276

ACTIVE NOT RECRUITING 80 participants

Reducing Opioid Prescription After Kidney Stone Removal Surgery

Mayo Clinic

NCT05353478

ACTIVE NOT RECRUITING NA 40 participants

Influence of Obesity on Endogenous Oxalate Synthesis

University of Alabama at Birmingham

NCT03704350

ACTIVE NOT RECRUITING NA 22 participants

Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers

University of Alabama at Birmingham

NCT04333745

ACTIVE NOT RECRUITING NA 20 participants

Dietary Oxalate and Innate Immunity in Kidney Stone Disease

University of Alabama at Birmingham

NCT04051346

ACTIVE NOT RECRUITING NA 14 participants

Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers

University of Alabama at Birmingham

NCT04633811

ACTIVE NOT RECRUITING NA 10 participants

Potassium Citrate and Crystal Light Lemonade

Northwestern University

NCT05389995

COMPLETED 477 participants

Evaluation of Infection in Obstructing Urolithiasis

University of Texas Southwestern Medical Center

NCT04332861

COMPLETED Phase 2 118 participants

Perioperative Pregabalin in Ureteroscopy

University of Missouri-Columbia

NCT04122196

COMPLETED NA 75 participants

MIP Versus PCNL for Kidney Stone Disease

University of California, San Diego

NCT04767919

COMPLETED NA 23 participants

Assessment of Endogenous Oxalate Synthesis

University of Alabama at Birmingham

NCT05229952

COMPLETED NA 18 participants

Standard vs Mini-PCNL for the Treatment of Stone Disease

The Cleveland Clinic

NCT04069013

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Named interventions

Most-linked intervention names on Kidney Stone records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Low Oxalate Diet Dietary supplement
2 trials
Initial clinical and laboratory evaluation Other
1 trials
PCNL Procedure
1 trials
Primed, continuous intravenous infusion of 13C2-oxalate Other
1 trials
Low-oxalate controlled diet Dietary supplement
1 trials
Pregabalin 300mg Drug
1 trials
Minimally Invasive Percutaneous Nephrolithotomy (MIP) Procedure
1 trials
Standard Percutaneous Nephrolithotomy (sPCNL) Procedure
1 trials

US sites by state

Facility locations filed on Kidney Stone trials. A trial with sites in several states counts in each.

Alabama 10 trials
Illinois 8 trials
Texas 4 trials
Ohio 3 trials
California 3 trials
Tennessee 2 trials
Missouri 2 trials
Kansas 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Kidney Stone page

29 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Kidney Stone condition card totals 29 registered trials; most-linked intervention Low Oxalate Diet; top US site state Alabama. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.