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ClinicalTrials.gov 15 recruiting now official registry

Kidney Stone clinical trials

Every US clinical trial registered for Kidney Stone — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

29 US clinical trials · 15 currently recruiting

The research picture

Kidney Stone has 29 registered US clinical trials, 15 of them open to new participants right now — about 52% of the total.

15
recruiting participants now
52%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
10
top sponsor: University of Alabama at Birmingham

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 184 participants

Access Sheath and Stent Trial

University of Michigan

NCT07297953

RECRUITING NA 168 participants

High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy

Northwestern University

NCT05006937

RECRUITING NA 150 participants

ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach

University of Kansas Medical Center

NCT06547632

RECRUITING NA 150 participants

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

Northwestern University

NCT06346483

RECRUITING NA 136 participants

Oxalate Formation From Ascorbic Acid

University of Alabama at Birmingham

NCT04603898

RECRUITING NA 90 participants

Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis

The Cleveland Clinic

NCT05993546

RECRUITING NA 80 participants

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

University of Alabama at Birmingham

NCT06331546

RECRUITING NA 80 participants

Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes

University of Kansas Medical Center

NCT06576661

RECRUITING NA 50 participants

Oxalate and Citrate

University of Chicago

NCT05334979

RECRUITING NA 48 participants

Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease

University of Alabama at Birmingham

NCT06210009

RECRUITING NA 40 participants

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06330246

RECRUITING 40 participants

Kidney Stone Inflammation

University of Chicago

NCT06436235

RECRUITING Early Phase 1 36 participants

NSAIDs Stent Study

Washington University School of Medicine

NCT03638999

RECRUITING NA 30 participants

GI Oxalate Absorption

University of Chicago

NCT05356000

RECRUITING NA 24 participants

Oxalate and Citrate in Humans - Response to Citrate

University of Chicago

NCT06944223

ACTIVE NOT RECRUITING 3,000 participants

A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System

Calyxo

NCT07225933

ACTIVE NOT RECRUITING NA 116 participants

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

SonoMotion

NCT05701098

ACTIVE NOT RECRUITING NA 82 participants

Dietary Oxalate and Immune Cell Function

University of Alabama at Birmingham

NCT03877276

ACTIVE NOT RECRUITING 80 participants

Reducing Opioid Prescription After Kidney Stone Removal Surgery

Mayo Clinic

NCT05353478

ACTIVE NOT RECRUITING NA 40 participants

Influence of Obesity on Endogenous Oxalate Synthesis

University of Alabama at Birmingham

NCT03704350

ACTIVE NOT RECRUITING NA 22 participants

Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers

University of Alabama at Birmingham

NCT04333745

ACTIVE NOT RECRUITING NA 20 participants

Dietary Oxalate and Innate Immunity in Kidney Stone Disease

University of Alabama at Birmingham

NCT04051346

ACTIVE NOT RECRUITING NA 14 participants

Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers

University of Alabama at Birmingham

NCT04633811

ACTIVE NOT RECRUITING NA 10 participants

Potassium Citrate and Crystal Light Lemonade

Northwestern University

NCT05389995

COMPLETED 477 participants

Evaluation of Infection in Obstructing Urolithiasis

University of Texas Southwestern Medical Center

NCT04332861

COMPLETED Phase 2 118 participants

Perioperative Pregabalin in Ureteroscopy

University of Missouri-Columbia

NCT04122196

COMPLETED NA 75 participants

MIP Versus PCNL for Kidney Stone Disease

University of California, San Diego

NCT04767919

COMPLETED NA 23 participants

Assessment of Endogenous Oxalate Synthesis

University of Alabama at Birmingham

NCT05229952

COMPLETED NA 18 participants

Standard vs Mini-PCNL for the Treatment of Stone Disease

The Cleveland Clinic

NCT04069013

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Kidney Stone Trial Landscape

ClinicalTrials.gov lists 29 US studies indexed under Kidney Stone, and 15 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Kidney Stone shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Kidney Stone is led by University of Alabama at Birmingham with 10 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 29 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Kidney Stone?

PlainTrial tracks 29 US clinical trials for Kidney Stone, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Kidney Stone?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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