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NCT07227467 · ClinicalTrials.gov registry record
Prospective Assessments Following Immediate Lymphatic Reconstruction
A clinical trial of Lymphatic Reconstruction, sponsored by University of Chicago.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT07227467 is a study of Lymphatic Reconstruction that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 100 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07227467, a study of Lymphatic Reconstruction, is actively recruiting participants, sponsored by University of Chicago.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema.(Chang et al. 2020) It involves the identification of lymphatic channels that are transected after lymph node dissection and microsurgical anastomosis of one or more lymphatic channel with a local recipient vein to re-direct upper extremity lymphatic drainage. Although ILR carries significant promise in prevention of lymphedema, there is a lack of high-level evidence supporting its efficacy because it is a novel surgical technique that is only offered at a few centers and not routinely covered by insurance carriers yet. The University of Chicago Comprehensive Cancer Center (UCCCC) is one of the busiest microsurgery centers performing this procedure, and, as a Lymphedema Center of Excellence, is in a unique position to investigate the efficacy of ILR in preventing lymphedema. In addition, the University has access to a world class microbiome research facility and colleagues. To our knowledge, there is no information on the skin microbiome of the axilla in patients undergoing treatment for breast cancer or those at risk for developing lymphedema. Further exploratory studies such as this in a diverse patient population may lead to practice changing research in our approach to lymphedema management and prevention.
Conditions Studied
Interventions
- OTHER patients who are candidates for immediate lymphatic reconstruction
Study Locations (1)
Illinois
- The University o Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2030-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07227467
The ClinicalTrials.gov registry entry for NCT07227467 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Lymphatic Reconstruction appearing as the primary indexed condition, and to 1 intervention - of which patients who are candidates for immediate lymphatic reconstruction is the first listed.
NCT07227467 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT07227467 about?
NCT07227467 is a clinical study titled "Prospective Assessments Following Immediate Lymphatic Reconstruction". Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema.(Chang et al. 2020) It involves the identification of lymphatic channels that are transected after lymph node dissection and microsurgic...
What is the current status of trial NCT07227467?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2025-12-01. Estimated completion is 2030-12.
What conditions does trial NCT07227467 study?
This clinical trial studies the following conditions: Lymphatic Reconstruction.
What interventions are being tested in trial NCT07227467?
The interventions under investigation include: patients who are candidates for immediate lymphatic reconstruction (OTHER).
Who is sponsoring clinical trial NCT07227467?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07227467 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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