University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 2 of 16

RECRUITING

Pathobiomes in Gut of Critically Ill Patients

NCT06822465

RECRUITING Phase 1

Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors

NCT06663072

RECRUITING

Hemodynamic ABI Monitor

NCT06725108

RECRUITING

Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA

NCT06650592

RECRUITING Phase 1

Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

NCT06639503

RECRUITING NA

Reducing Disparities in Urinary Control Symptoms for Minority Women

NCT06798311

RECRUITING

Immune Status After Being on Call for 24 Hrs

NCT06636318

RECRUITING NA

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

NCT06094478

RECRUITING Phase 1

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

NCT06291987

RECRUITING Phase 1

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

NCT06207123

RECRUITING NA

A Novel Intervention for Weight Loss in Young Adults

NCT06230744

RECRUITING Phase 1

Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population

NCT06538584

RECRUITING NA

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

NCT06397456

RECRUITING Phase 2

Communication Bridge 3 Study

NCT06191198

RECRUITING NA

J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations

NCT06477588

RECRUITING NA

Comprehensive Geriatric Assessment (Tests) for Bladder Cancer Participants Undergoing Radical Cystectomy

NCT06427824

RECRUITING NA

Brain Function Monitoring During Surgery

NCT06619730

RECRUITING NA

Informing Pain Treatment Using Pharmacogenomic Analysis

NCT06511401

RECRUITING Phase 1

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

NCT05108870

RECRUITING NA

Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder

NCT06479447

RECRUITING NA

Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

NCT06525818

RECRUITING NA

Dime La VerDAD: Verify, Debunk, and Disseminate

NCT06417762

RECRUITING

Kidney Stone Inflammation

NCT06436235

RECRUITING Phase 1

Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery

NCT06349590

RECRUITING

Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)

NCT06705803

RECRUITING

Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair

NCT06551077

RECRUITING NA

Get Fit for Function

NCT06359652

RECRUITING

Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation

NCT06317701

RECRUITING

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

NCT06950788

RECRUITING Phase 1

Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

NCT06305286

RECRUITING NA

Feasibility of a Dog Training Therapy Program in UC Outpatient Youth Receiving Psychiatric Services

NCT05788783

RECRUITING Early Phase 1

Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone

NCT06063538

RECRUITING NA

Durometer for Measuring Uterine Tone

NCT06284421

RECRUITING NA

Oxygenation in Vascular Lesions of the Colon

NCT06230731

RECRUITING Early Phase 1

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

NCT06171152

RECRUITING NA

Quantitative Assessment of Autologous Fat Transfer

NCT06343831

RECRUITING NA

Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life

NCT06171269

RECRUITING

Combining Biomarkers and Electronic Risk Scores to Predict AKI in Hospitalized Patients

NCT05988658

RECRUITING NA

Video Training Supplementation for Patients Discharged on Home Parental Nutrition

NCT06169774

RECRUITING Phase 1

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

NCT06005324

RECRUITING

Biobank Cardiac Surgery

NCT06747806

RECRUITING NA

Percutaneous Nerve Evaluation Trial Time

NCT06226220

RECRUITING NA

Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials

NCT05886764

RECRUITING

Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis

NCT06781463

RECRUITING Phase 2

Frameless Stereotactic Radiosurgery for Intact Brain Metastases

NCT02747303

RECRUITING NA

Chicago Asthma School-Directed Child-Centered Assessment and Dissemination of Evidence

NCT06320210

RECRUITING NA

PrEP Optimization Among Women to Enhance Retention and Uptake

NCT05626452

RECRUITING NA

Tissue Destruction and Healing in Celiac Disease

NCT05680012

RECRUITING Early Phase 1

Cardiac Power Output in Cardiogenic Shock Patients

NCT05700617

RECRUITING Phase 4

A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

NCT06008860

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Chicago pipeline card: 796 registered trials from official public datasets.Report a data error.