Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07672301 · ClinicalTrials.gov registry record · Phase 1
Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty
A Phase 1 study, sponsored by University of Chicago.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 150
- Enrollment target
NCT07672301 is a Phase 1 study that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 150 participants.
The verdict
NCT07672301, a Phase 1 study, is actively recruiting participants, sponsored by University of Chicago.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 150 participants
- Enrollment target
Study Summary
The purpose of this study is to compare same-day discharge rates and recovery outcomes across an adult patient population undergoing elective Total Knee Arthroplasty (TKA), and randomized to receive either spinal block anesthesia or Total IntraVenous Anesthesia (TIVA). Primary Aim: assess same-day discharge rates between study arms (TIVA vs spinal). Secondary Aim: Postoperative comparison of recovery during PostOperative Anesthesia Care Unit (PACU) admission, diagnostic assessment scores; outcomes related to cognition, hemodynamic stability, pain, nausea and vomiting; analysis of IntraOperative electroencephalogram (EEG) monitoring metrics, e.g., total suppression time, average Bi-spectral Index monitor (BIS) value, Spectral Edge Frequency (SEF); ability for Physical Therapy (PT) evaluation prior to discharge; longterm-followup (LTFU), hospital readmission, return to surgery, etc.; adverse event (AE) monitoring.
Interventions
- DEVICE Electroencephalogram (EEG)
- COMBINATION_PRODUCT Total IntraVenous Anesthesia (TIVA)
- COMBINATION_PRODUCT Spinal-Block
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-03-11 |
| Est. Completion | 2028-06 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07672301
The ClinicalTrials.gov registry entry for NCT07672301 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Electroencephalogram (EEG) is the first listed.
NCT07672301 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07672301 about?
NCT07672301 is a clinical study titled "Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty". The purpose of this study is to compare same-day discharge rates and recovery outcomes across an adult patient population undergoing elective Total Knee Arthroplasty (TKA), and randomized to receive either spinal block anesthesia or Total IntraVenous Anesthesia (TIVA). Primary Aim: assess same-day ...
What is the current status of trial NCT07672301?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 150 participants. The study started on 2026-03-11. Estimated completion is 2028-06.
What interventions are being tested in trial NCT07672301?
The interventions under investigation include: Electroencephalogram (EEG) (DEVICE), Total IntraVenous Anesthesia (TIVA) (COMBINATION_PRODUCT), Spinal-Block (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT07672301?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.