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NCT07126509 · ClinicalTrials.gov registry record · NA

Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

A NA study of Mesothelioma and Mesothelioma, Malignant, sponsored by University of Chicago.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT07126509: Recruiting NA study of Mesothelioma and Mesothelioma, Malignant, sponsored by University of Chicago.

NCT07126509 is a NA study of Mesothelioma and Mesothelioma, Malignant that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 30 participants, below the 197-participant average among 46 other Mesothelioma trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07126509, a NA study of Mesothelioma and Mesothelioma, Malignant, is actively recruiting participants, sponsored by University of Chicago.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Purpose of the study: The main purpose of this research study is to see if a surgery procedure (limited partial pleurectomy and decortication) helps symptoms in people who have cancer that is unresectable that might not be able to be removed completely. This is called unresectable cancer. This study will also help the research team learn more about the types of symptoms and quality of life for people who have undergone this surgery, the number of complications following , and the time from surgery to starting other therapy. Th e study team also wants to see see the overall survival of people who have had this procedure as part of their care. What will be done as part of research on this study: * Surgery (Partial Pleurectomy - surgery to remove lining of lungs) * The research team will also ask study participants questions about their symptoms through questionnaires at certain times after surgery. How long this study will last: Participation in this research (pre-surgery, surgery and follow-up) will last for about 2 years. Confidentiality: All personal information will be kept confidential, and data will be used only for research purposes. Contact Information: For more information about this study, please contact PhaseIICRA@medicine.bsd.uchicago.edu

Primary Outcome

The primary objective is to assess the post-operative disease-related symptom burden in participants undergoing partial pleurectomy and decortication for borderline or unresectable pleural mesothelioma, as measured by the mesothelioma-specific Lung Cancer Symptom Scale Average Symptom Burden Index (LCSS-meso ASBI) at 3 months post-surgery.

Interventions

  • PROCEDURE Partial Pleurectomy

Study Locations (1)

Illinois

  • University of Chicago Medicine Comprehensive Cancer Center - Chicago

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-12-02
Est. Completion 2028-12-01
Phase NA
University of Chicago

796 total trials

What NCT07126509 shows while recruiting

NCT07126509 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 197-participant average among 46 other Mesothelioma trials with a reported enrollment target (85% lower).

The record links to 5 conditions, with Mesothelioma appearing as the primary indexed condition, and to 1 intervention - of which Partial Pleurectomy is the first listed.

NCT07126509 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT07126509 about?

NCT07126509 is a clinical study titled "Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma". Purpose of the study: The main purpose of this research study is to see if a surgery procedure (limited partial pleurectomy and decortication) helps symptoms in people who have cancer that is unresectable that might not be able to be removed completely. This is called unresectable cancer. This study...

What is the current status of trial NCT07126509?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-12-02. Estimated completion is 2028-12-01.

What conditions does trial NCT07126509 study?

This clinical trial studies the following conditions: Mesothelioma, Mesothelioma, Malignant, Mesotheliomas Pleural, Mesothelioma; Lung, Mesothelioma Malignant Advanced.

What interventions are being tested in trial NCT07126509?

The interventions under investigation include: Partial Pleurectomy (PROCEDURE).

Who is sponsoring clinical trial NCT07126509?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07126509 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Mesothelioma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07126509's enrollment target sits among peer trials

30 39th of 46 higher than 7 of 46 other Mesothelioma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Mesothelioma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07126509, the US trial registry maintained by the National Library of Medicine. NCT07126509 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.