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NCT03225677 · ClinicalTrials.gov registry record
Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis
A clinical trial of Cirrhosis, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT03225677: Recruiting study of Cirrhosis, sponsored by The Cleveland Clinic.
NCT03225677 is a study of Cirrhosis that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 20 participants, below the 90,409-participant average among 53 other Cirrhosis trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03225677, a study of Cirrhosis, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine the rate and mechanisms of skeletal muscle protein synthesis and breakdown in cirrhotic patients by using multiple tracers and single muscle biopsies.
Primary Outcome
Fractional synthesis rate (FSR)for each patient is measured by the rate of tracer incorporation from the MIF pool to the bound pool.
Conditions Studied
Interventions
- PROCEDURE blood draw and muscle biopsy
Study Locations (1)
Ohio
- Cleveland Clinic Foundation - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2017-08-03 |
| Est. Completion | 2027-09-30 |
What NCT03225677 shows while recruiting
NCT03225677 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 90,409-participant average among 53 other Cirrhosis trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Cirrhosis appearing as the primary indexed condition, and to 1 intervention - of which blood draw and muscle biopsy is the first listed.
NCT03225677 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT03225677 about?
NCT03225677 is a clinical study titled "Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis". To determine the rate and mechanisms of skeletal muscle protein synthesis and breakdown in cirrhotic patients by using multiple tracers and single muscle biopsies.
What is the current status of trial NCT03225677?
This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2017-08-03. Estimated completion is 2027-09-30.
What conditions does trial NCT03225677 study?
This clinical trial studies the following conditions: Cirrhosis.
What interventions are being tested in trial NCT03225677?
The interventions under investigation include: blood draw and muscle biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT03225677?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03225677 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cirrhosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03225677's enrollment target sits among peer trials
20 44th of 53 higher than 8 of 53 other Cirrhosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cirrhosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis
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-
Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease
RECRUITING · Phase 1
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