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NCT04578392 · ClinicalTrials.gov registry record · NA

MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)

A NA study of Crohn Disease, sponsored by The Cleveland Clinic.

Recruiting
Registry status
NA
Development phase
181
Enrollment target
7
Study locations

NCT04578392 is a NA study of Crohn Disease that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 181 participants, below the 203-participant average among 71 other Crohn Disease trials with a reported enrollment target (11% lower). The trial reports 7 study locations across 6 states.

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The verdict

NCT04578392, a NA study of Crohn Disease, is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
NA
Development phase
181 participants
Enrollment target
7
Study locations

Study Summary

Study description - Patients will be randomized according to post-operative recurrence risk to either a high ligation of ileocolic artery or mesenteric sparing ileocolic resection for terminal ileal Crohn's disease. The primary endpoint 6-month endoscopic recurrence. Endpoints - Primary endpoint; 6 months Secondary endpoints at 1 and 5 years post ileocecal resection Study population - Adult Crohn's disease patients with medically refractory terminal ileal Crohn's disease undergoing a primary ileocecal resection. Study sites - Multicenter international study Description of study intervention - Randomized control trial of two operative techniques Operative approach of a high ligation of ileocolic artery as compared to mesenteric sparing for a primary ileocolic resection Participate duration - 5 years

Conditions Studied

Crohn Disease

Interventions

  • PROCEDURE high ligation of ileocolic artery
  • PROCEDURE mesenteric sparing

Study Locations (7)

California

  • Cedars-Sinai Hospital System - Los Angeles
  • Stanford University School of Medicine - Stanford

Florida

  • Cleveland Clinic Florida - Weston

Ohio

  • Cleveland Clinic - Cleveland

Ontario

  • Mt. Sinai - Toronto

Milano

  • Humanitas - Rozzano

Middlesex

  • St Mark's Hospital and Academic Institution - Harrow

Trial Details

FieldValue
Enrollment Target 181 participants
Start Date 2020-07-28
Est. Completion 2027-12-31
Phase NA

Sponsor

The Cleveland Clinic

688 total trials

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What the Registry Record Tells You About NCT04578392

The ClinicalTrials.gov registry entry for NCT04578392 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 181 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 203-participant average among 71 other Crohn Disease trials with a reported enrollment target (11% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Crohn Disease appearing as the primary indexed condition, and to 2 interventions - of which high ligation of ileocolic artery is the first listed.

NCT04578392 reports 7 study locations spanning 6 distinct geographic areas - top geographies include California, Florida, Ohio.

Frequently Asked Questions

What is clinical trial NCT04578392 about?

NCT04578392 is a clinical study titled "MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)". Study description - Patients will be randomized according to post-operative recurrence risk to either a high ligation of ileocolic artery or mesenteric sparing ileocolic resection for terminal ileal Crohn's disease. The primary endpoint 6-month endoscopic recurrence. Endpoints - Primary endpoint; 6...

What is the current status of trial NCT04578392?

This trial is currently recruiting. It is a NA study. The enrollment target is 181 participants. The study started on 2020-07-28. Estimated completion is 2027-12-31.

What conditions does trial NCT04578392 study?

This clinical trial studies the following conditions: Crohn Disease.

What interventions are being tested in trial NCT04578392?

The interventions under investigation include: high ligation of ileocolic artery (PROCEDURE), mesenteric sparing (PROCEDURE).

Who is sponsoring clinical trial NCT04578392?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04578392 being conducted?

This trial has 7 study locations across California, Florida, Ohio, Ontario, Milano. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.