Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06193512 · ClinicalTrials.gov registry record · NA
Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study
A NA study of Mechanical Ventilation Complication and Oral Bacterial Infection, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT06193512: Recruiting NA study of Mechanical Ventilation Complication and Oral Bacterial Infection, sponsored by The Cleveland Clinic.
NCT06193512 is a NA study of Mechanical Ventilation Complication and Oral Bacterial Infection that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 21 participants, below the 1,186-participant average among 8 other Mechanical Ventilation Complication trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06193512, a NA study of Mechanical Ventilation Complication and Oral Bacterial Infection, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
We propose a randomized pilot/feasibility study comparing oral care treatment as usual (TAU) with Swiftsure SwishKit plus oral care TAU on the presence and magnitude of bacterial load in the oropharyngeal space in orotracheally intubated patients. The trial will be conducted with IRB approval and written consent from patient or its legal representative.
Primary Outcome
Incidence of the presence of bacterial load in the oropharyngeal space from culture and qPCR of the five target pathogens: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.
Conditions Studied
Interventions
- DEVICE SwishKit + Oral care treatment as usual
- PROCEDURE Oral care treatment as usual
Study Locations (1)
Ohio
- Cleveland Clinic Foundation - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2024-03-08 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
What NCT06193512 shows while recruiting
NCT06193512 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,186-participant average among 8 other Mechanical Ventilation Complication trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Mechanical Ventilation Complication appearing as the primary indexed condition, and to 2 interventions - of which SwishKit + Oral care treatment as usual is the first listed.
NCT06193512 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06193512 about?
NCT06193512 is a clinical study titled "Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study". We propose a randomized pilot/feasibility study comparing oral care treatment as usual (TAU) with Swiftsure SwishKit plus oral care TAU on the presence and magnitude of bacterial load in the oropharyngeal space in orotracheally intubated patients. The trial will be conducted with IRB approval and wr...
What is the current status of trial NCT06193512?
This trial is currently recruiting. It is a NA study. The enrollment target is 21 participants. The study started on 2024-03-08. Estimated completion is 2025-12-31.
What conditions does trial NCT06193512 study?
This clinical trial studies the following conditions: Mechanical Ventilation Complication, Oral Bacterial Infection.
What interventions are being tested in trial NCT06193512?
The interventions under investigation include: SwishKit + Oral care treatment as usual (DEVICE), Oral care treatment as usual (PROCEDURE).
Who is sponsoring clinical trial NCT06193512?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06193512 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mechanical Ventilation Complication
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06193512's enrollment target sits among peer trials
21 7th of 8 higher than 2 of 8 other Mechanical Ventilation Complication trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mechanical Ventilation Complication trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy
RECRUITING · NA
-
Behavioral Economic & Staffing Strategies in the ICU
RECRUITING · NA
-
CT for Personalized Mechanical Ventilation
ACTIVE NOT RECRUITING · NA
-
Endotracheal Tube Securement Study
COMPLETED · NA
-
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).
RECRUITING
-
Using Ultrasound to Study Respiratory Muscle Function in Critically Ill Patients
COMPLETED
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02447874 · 21 participants · Phase 1
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
- NCT03826992 · 21 participants · Phase 1
Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia
- NCT04107077 · 21 participants · Phase 2
Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer
- NCT04158635 · 21 participants · Phase 1
Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI