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NCT06789809 · ClinicalTrials.gov registry record · NA

Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue

A NA study of Aortic Aneurysm, sponsored by The Cleveland Clinic.

Recruiting
Registry status
NA
Development phase
35
Enrollment target
1
Study location

NCT06789809 is a NA study of Aortic Aneurysm that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 35 participants, below the 637-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06789809, a NA study of Aortic Aneurysm, is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
NA
Development phase
35 participants
Enrollment target
1
Study location

Study Summary

Aortic aneurysm patients benefit from exercise yet patients and physicians do not know a safe level. Cardiac MRI (CMR) is the most comprehensive imaging modality for phenotypic evaluation of patients with cardiac disease but it has not been used to study aneurysm patients. The purpose of this project is use exercise CMR to understand regional aortic function and quantify aortic elasticity in these populations while exercising. This project will correlate the exercise CMR data with the biomechanical properties of the patient's aortic tissue, including epiaortic ultrasound and TEE performed during aortic repair, and explanted aortic specimens subjected to ex vivo uniaxial tensile testing. Correlating this data with aortic response to exercise will allow us to understand how aortic size, in vivo circumferential strain values, ex vivo aortic efficiency and mechanical failure all relate to exercise physiology.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST Exercise MRI

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2023-11-23
Est. Completion 2029-03-31
Phase NA

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT06789809

The ClinicalTrials.gov registry entry for NCT06789809 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 637-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (95% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Aortic Aneurysm appearing as the primary indexed condition, and to 1 intervention - of which Exercise MRI is the first listed.

NCT06789809 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06789809 about?

NCT06789809 is a clinical study titled "Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue". Aortic aneurysm patients benefit from exercise yet patients and physicians do not know a safe level. Cardiac MRI (CMR) is the most comprehensive imaging modality for phenotypic evaluation of patients with cardiac disease but it has not been used to study aneurysm patients. The purpose of this projec...

What is the current status of trial NCT06789809?

This trial is currently recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2023-11-23. Estimated completion is 2029-03-31.

What conditions does trial NCT06789809 study?

This clinical trial studies the following conditions: Aortic Aneurysm.

What interventions are being tested in trial NCT06789809?

The interventions under investigation include: Exercise MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT06789809?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06789809 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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