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NCT06789809 · ClinicalTrials.gov registry record · NA
Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue
A NA study of Aortic Aneurysm, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT06789809: Recruiting NA study of Aortic Aneurysm, sponsored by The Cleveland Clinic.
NCT06789809 is a NA study of Aortic Aneurysm that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 35 participants, below the 637-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06789809, a NA study of Aortic Aneurysm, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Aortic aneurysm patients benefit from exercise yet patients and physicians do not know a safe level. Cardiac MRI (CMR) is the most comprehensive imaging modality for phenotypic evaluation of patients with cardiac disease but it has not been used to study aneurysm patients. The purpose of this project is use exercise CMR to understand regional aortic function and quantify aortic elasticity in these populations while exercising. This project will correlate the exercise CMR data with the biomechanical properties of the patient's aortic tissue, including epiaortic ultrasound and TEE performed during aortic repair, and explanted aortic specimens subjected to ex vivo uniaxial tensile testing. Correlating this data with aortic response to exercise will allow us to understand how aortic size, in vivo circumferential strain values, ex vivo aortic efficiency and mechanical failure all relate to exercise physiology.
Primary Outcome
Absolute change in arterial volume for a change in pressure
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Exercise MRI
Study Locations (1)
Ohio
- Cleveland Clinic - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2023-11-23 |
| Est. Completion | 2029-03-31 |
| Phase | NA |
What NCT06789809 shows while recruiting
NCT06789809 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 637-participant average among 14 other Aortic Aneurysm trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Aortic Aneurysm appearing as the primary indexed condition, and to 1 intervention - of which Exercise MRI is the first listed.
NCT06789809 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06789809 about?
NCT06789809 is a clinical study titled "Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue". Aortic aneurysm patients benefit from exercise yet patients and physicians do not know a safe level. Cardiac MRI (CMR) is the most comprehensive imaging modality for phenotypic evaluation of patients with cardiac disease but it has not been used to study aneurysm patients. The purpose of this projec...
What is the current status of trial NCT06789809?
This trial is currently recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2023-11-23. Estimated completion is 2029-03-31.
What conditions does trial NCT06789809 study?
This clinical trial studies the following conditions: Aortic Aneurysm.
What interventions are being tested in trial NCT06789809?
The interventions under investigation include: Exercise MRI (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06789809?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06789809 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aortic Aneurysm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06789809's enrollment target sits among peer trials
35 10th of 14 higher than 5 of 14 other Aortic Aneurysm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aortic Aneurysm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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