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NCT05025865 · ClinicalTrials.gov registry record · Early Phase 1

HA35 Acute Alcohol Study

A Early Phase 1 study of Healthy (Controls), sponsored by The Cleveland Clinic.

Recruiting
Registry status
Early Phase 1
Development phase
24
Enrollment target
1
Study location

NCT05025865: Recruiting Early Phase 1 study of Healthy (Controls), sponsored by The Cleveland Clinic.

NCT05025865 is a Early Phase 1 study of Healthy (Controls) that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 24 participants, below the 120-participant average among 16 other Healthy (Controls) trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05025865, a Early Phase 1 study of Healthy (Controls), is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
Early Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

Eligible subjects will be asked to take a placebo/treatment capsule for a total of 3 days and then participate in a study visit on the fourth day. This study visit will include a medical exam, clinical labs, questionnaires, body composition measurements, and urine and stool collections. Additionally, participants will consume a sugar cocktail to measure their gut permeability, participate in an acute ethanol challenge, and undergo two muscle biopsies. The study will take approximately 3-4 hours and a designated driver will need to drive the participant home. On the fifth day, you will be asked to return to drop of the 24-hour urine collection.

Primary Outcome

change in units/liter (U/L)

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Sodium Hyaluronate

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2022-02-01
Est. Completion 2027-10-01
Phase Early Phase 1
The Cleveland Clinic

688 total trials

What NCT05025865 shows while recruiting

NCT05025865 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 120-participant average among 16 other Healthy (Controls) trials with a reported enrollment target (80% lower).

The record links to 1 condition, with Healthy (Controls) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05025865 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT05025865 about?

NCT05025865 is a clinical study titled "HA35 Acute Alcohol Study". Eligible subjects will be asked to take a placebo/treatment capsule for a total of 3 days and then participate in a study visit on the fourth day. This study visit will include a medical exam, clinical labs, questionnaires, body composition measurements, and urine and stool collections. Additionally...

What is the current status of trial NCT05025865?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 24 participants. The study started on 2022-02-01. Estimated completion is 2027-10-01.

What conditions does trial NCT05025865 study?

This clinical trial studies the following conditions: Healthy (Controls).

What interventions are being tested in trial NCT05025865?

The interventions under investigation include: Placebo (DRUG), Sodium Hyaluronate (DRUG).

Who is sponsoring clinical trial NCT05025865?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05025865 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy (Controls)

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05025865's enrollment target sits among peer trials

24 16th of 16 higher than 1 of 16 other Healthy (Controls) trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy (Controls) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05025865, the US trial registry maintained by the National Library of Medicine. NCT05025865 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.