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NCT02016430 · ClinicalTrials.gov registry record · NA

Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)

A NA study of Cardiovascular Risk Factor and Dietary Modification, sponsored by The Cleveland Clinic.

Recruiting
Registry status
NA
Development phase
170
Enrollment target
1
Study location

NCT02016430 is a NA study of Cardiovascular Risk Factor and Dietary Modification that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 170 participants, below the 3,063-participant average among 31 other Cardiovascular Risk Factor trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02016430, a NA study of Cardiovascular Risk Factor and Dietary Modification, is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
NA
Development phase
170 participants
Enrollment target
1
Study location

Study Summary

Our group has recently identified the association between gut-flora-mediated carnitine and phosphatidylcholine metabolism, specifically trimethylamine-N-oxide (TMAO), and cardiovascular risk. This study investigates the ability for dietary intervention to modulate TMAO levels.

Conditions Studied

Cardiovascular Risk Factor Dietary Modification

Interventions

  • BEHAVIORAL MeLT Dietary intervention
  • BEHAVIORAL TLC Dietary intervention
  • BEHAVIORAL MeLT dietary intervention with TMAO

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 170 participants
Start Date 2014-04-04
Est. Completion 2026-12
Phase NA

Sponsor

The Cleveland Clinic

688 total trials

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What the Registry Record Tells You About NCT02016430

The ClinicalTrials.gov registry entry for NCT02016430 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 170 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,063-participant average among 31 other Cardiovascular Risk Factor trials with a reported enrollment target (94% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cardiovascular Risk Factor appearing as the primary indexed condition, and to 3 interventions - of which MeLT Dietary intervention is the first listed.

NCT02016430 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT02016430 about?

NCT02016430 is a clinical study titled "Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)". Our group has recently identified the association between gut-flora-mediated carnitine and phosphatidylcholine metabolism, specifically trimethylamine-N-oxide (TMAO), and cardiovascular risk. This study investigates the ability for dietary intervention to modulate TMAO levels.

What is the current status of trial NCT02016430?

This trial is currently recruiting. It is a NA study. The enrollment target is 170 participants. The study started on 2014-04-04. Estimated completion is 2026-12.

What conditions does trial NCT02016430 study?

This clinical trial studies the following conditions: Cardiovascular Risk Factor, Dietary Modification.

What interventions are being tested in trial NCT02016430?

The interventions under investigation include: MeLT Dietary intervention (BEHAVIORAL), TLC Dietary intervention (BEHAVIORAL), MeLT dietary intervention with TMAO (BEHAVIORAL).

Who is sponsoring clinical trial NCT02016430?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02016430 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.