National Institute of Neurological Disorders and Stroke (NINDS)
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, National Institute of Neurological Disorders and Stroke (NINDS) sits in the top decile of US sponsors by registered trial count (#61 of 15,742 sponsors by registered trial count).
National Institute of Neurological Disorders and Stroke (NINDS): 567 sponsored US clinical trials, 48 recruiting.
National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.
Top-decile sponsor footprint
National Institute of Neurological Disorders and Stroke (NINDS) ranks in the top decile of sponsors by registered trial count (#61 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
467 of 508 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
567 total, page 1 of 12
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
NCT07416188
Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study
NCT07511049
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
NCT06615973
Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques
NCT07137442
Predicting Future Errors During Skill Performance
NCT06707207
DDAVP for Pituitary Adenoma
NCT04569591
A Prospective Natural History and Outcome Measure Validation Study of Congenital Myasthenic Syndromes
NCT06630650
Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort
NCT06472622
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
NCT06577467
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
NCT02531880
Data Collection of Standard Care of Patients in the EMG Section
NCT05041387
Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology
NCT06203626
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy
NCT05849467
NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)
NCT05375812
Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects
NCT05604534
Natural History Protocol for Movement Disorders
NCT05413291
Investigational Use of Neuromuscular Ultrasound
NCT05237973
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health
NCT04573062
Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)
NCT04944940
Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis
NCT04799288
The Beneficial Effects of Naps on Motor Learning
NCT04312126
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing
NCT04394871
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
NCT03678389
Influence of Brain Oscillation-Dependent TMS on Motor Function
NCT03288220
Investigating Epilepsy: Screening and Evaluation
NCT03478852
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
NCT03225144
Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques
NCT02784210
Pathological Basis of MRI Signal Changes in Multiple Sclerosis
NCT02659956
Tumor Related Epilepsy
NCT02639325
Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
NCT02629107
Inflammatory and Infectious Diseases of the Nervous System
NCT02435810
Deep Brain Stimulation Therapy in Movement Disorders
NCT02119611
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
NCT02107989
Thinking and Memory Problems in People With HIV
NCT01875588
Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers
NCT01900132
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
NCT01730131
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
NCT01568658
Deep Brain Stimulation Surgery for Movement Disorders
NCT01581580
Surgery as a Treatment for Medically Intractable Epilepsy
NCT01273129
Natural History Study of Patients With Neurofibromatosis Type 2
NCT00598351
Evaluation and Treatment of Neurosurgical Disorders
NCT00060541
Phenotype/Genotype Correlations in Movement Disorders
NCT00018889
Natural History of Stroke: Cause and Development
NCT00009243
Study of New Magnetic Resonance Imaging Methods of the Brain
NCT00004577
Study of Inherited Neurological Disorders
NCT00004568
Evaluation of Patients With HAM/TSP
NCT00001778
Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
NCT00001248
Botulinum Toxin for the Treatment of Involuntary Movement Disorders
NCT00001208
Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)
NCT07204977
Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
NCT05155059
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 80 |
| Phase 2 | 78 |
| Phase 3 | 11 |
| Phase 4 | 5 |
Therapeutic Areas
What is open in the National Institute of Neurological Disorders and Stroke (NINDS) pipeline
48 recruiting of 567 indexed (8% open); 467 completed (82%).
Phase mix: 16 late (III/IV) vs 158 early (I/II) (early-phase heavy).
Top condition: Healthy (23 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
National Institute of Neurological Disorders and Stroke (NINDS): open-pipeline peers nationwide
Peers matched on 567 registered trials and 8% open enrollment, not the therapeutic-area sidebar.
National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 567 trials (± recruiting share)
- Children's Hospital Medical Center, Cincinnati · 571 trials · 19% recruiting
- University of Maryland, Baltimore · 560 trials · 18% recruiting
- Amgen · 558 trials · 10% recruiting
- Merck Sharp & Dohme · 558 trials · 22% recruiting
Sponsors near 8% open enrollment (± trial volume)
- National Jewish Health · 8% recruiting · 83 trials
- ACADIA Pharmaceuticals · 9% recruiting · 35 trials
- Texas Tech University Health Sciences Center, El Paso · 9% recruiting · 35 trials
- Boehringer Ingelheim · 8% recruiting · 515 trials
Related
What to do with this National Institute of Neurological Disorders and Stroke (NINDS) page
567 registered trials is a research-attention snapshot, not an endorsement of National Institute of Neurological Disorders and Stroke (NINDS) or any single study.
- 48 of National Institute of Neurological Disorders and Stroke (NINDS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Healthy is the condition National Institute of Neurological Disorders and Stroke (NINDS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
National Institute of Neurological Disorders and Stroke (NINDS) pipeline card: 567 registered trials from official public datasets.Report a data error.