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NCT07545759 · ClinicalTrials.gov registry record · Phase 2

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

A Phase 2 study, sponsored by Eli Lilly and Company.

Recruiting
Registry status
Phase 2
Development phase
531
Enrollment target

NCT07545759 is a Phase 2 study that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 531 participants.

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The verdict

NCT07545759, a Phase 2 study, is actively recruiting participants, sponsored by Eli Lilly and Company.

RECRUITING
Registry status
Phase 2
Development phase
531 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated, what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Diarrhea (IBS-D). The study drug will be administered subcutaneously (SC) (under the skin) when compared with placebo. The study will last approximately 35 weeks.

Interventions

  • DRUG Placebo
  • DRUG LY3537031

Trial Details

FieldValue
Enrollment Target 531 participants
Start Date 2026-05-06
Est. Completion 2027-11
Phase Phase 2

Sponsor

Eli Lilly and Company

1,341 total trials

What the Registry Record Tells You About NCT07545759

The ClinicalTrials.gov registry entry for NCT07545759 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 531 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07545759 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07545759 about?

NCT07545759 is a clinical study titled "A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)". The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated, what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Diarrhea (IBS-D). The study drug will be administered subcutaneously (SC) (under the skin) when compared with...

What is the current status of trial NCT07545759?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 531 participants. The study started on 2026-05-06. Estimated completion is 2027-11.

What interventions are being tested in trial NCT07545759?

The interventions under investigation include: Placebo (DRUG), LY3537031 (DRUG).

Who is sponsoring clinical trial NCT07545759?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.