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NCT07226843 · ClinicalTrials.gov registry record · Phase 1
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
A Phase 1 study, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 460
- Enrollment target
NCT07226843: Recruiting Phase 1 study, sponsored by Eli Lilly and Company.
NCT07226843 is a Phase 1 study that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 460 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (667% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07226843, a Phase 1 study, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 460 participants
- Enrollment target
Study Summary
The main purpose of this study is to evaluate safety and efficacy, and measure how much LY4584180 gets into the bloodstream and how long it takes the body to eliminate it in patients with previously treated blood cancers. For each participant, the study could last about 9 months or possibly longer including screening.
Primary Outcome
Number of Dose-Limiting Toxicities (DLTs) and DLT-Equivalent Toxicities
Interventions
- DRUG Rituximab
- DRUG LY4584180
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 460 participants |
| Start Date | 2026-04-17 |
| Est. Completion | 2030-02 |
| Phase | Phase 1 |
What NCT07226843 shows while recruiting
NCT07226843 is an interventional study that assigns participants to a tested intervention. The registered 460 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (667% higher).
The record links to 0 conditions, and to 2 interventions - of which Rituximab is the first listed.
NCT07226843 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07226843 about?
NCT07226843 is a clinical study titled "A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers". The main purpose of this study is to evaluate safety and efficacy, and measure how much LY4584180 gets into the bloodstream and how long it takes the body to eliminate it in patients with previously treated blood cancers. For each participant, the study could last about 9 months or possibly longer i...
What is the current status of trial NCT07226843?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 460 participants. The study started on 2026-04-17. Estimated completion is 2030-02.
What interventions are being tested in trial NCT07226843?
The interventions under investigation include: Rituximab (DRUG), LY4584180 (DRUG).
Who is sponsoring clinical trial NCT07226843?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07226843's enrollment target sits among peer trials
460 53rd of 2000 higher than 1,947 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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