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NCT07269210 · ClinicalTrials.gov registry record · Phase 2
A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia
A Phase 2 study of Severe Hypertriglyceridemia, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 20
- Study locations
NCT07269210: Recruiting Phase 2 study of Severe Hypertriglyceridemia, sponsored by Eli Lilly and Company.
NCT07269210 is a Phase 2 study of Severe Hypertriglyceridemia that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 60 participants, below the 418-participant average among 8 other Severe Hypertriglyceridemia trials with a reported enrollment target (86% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07269210, a Phase 2 study of Severe Hypertriglyceridemia, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the safety and efficacy of solbinsiran in lowering triglycerides and other lipid measures compared to placebo in participants with severe hypertriglyceridemia. Participants will receive two subcutaneous injections.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Solbinsiran
Study Locations (20)
California
- National Heart Institute - Beverly Hills
- Ark Clinical Research - Long Beach
- Catalina Research Institute, LLC - Montclair
- Valley Clinical Trials, Inc. - Northridge
Florida
- Northeast Research Institute - Downtown Office - Jacksonville
- Novera Clinical Research - Miami
- Inpatient Research Clinic - Miami Lakes
- Clinical Site Partners, LLC dba Flourish Research - Winter Park
Arizona
- Axsendo Clinical Research - Peak Heart & Vascular - Phoenix - Phoenix
- Synexus Clinical Research US, Inc./Orange Grove Family Practice - Tucson
New York
- Weill Cornell Medical College - New York
- Icahn School of Medicine at Mount Sinai - New York
Connecticut
- CMR of Greater New Haven, LLC - Hamden
Illinois
- Great Lakes Clinical Trials - Ravenswood - Chicago
Indiana
- Investigators Research Group - Brownsburg
Kentucky
- Saint Elizabeth Healthcare - Saint Elizabeth Covington Hospital - Covington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-12-08 |
| Est. Completion | 2027-08 |
| Phase | Phase 2 |
What NCT07269210 shows while recruiting
NCT07269210 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 418-participant average among 8 other Severe Hypertriglyceridemia trials with a reported enrollment target (86% lower).
The record links to 1 condition, with Severe Hypertriglyceridemia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07269210 names 20 study sites across 12 states, led by California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT07269210 about?
NCT07269210 is a clinical study titled "A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia". The purpose of this study is to evaluate the safety and efficacy of solbinsiran in lowering triglycerides and other lipid measures compared to placebo in participants with severe hypertriglyceridemia. Participants will receive two subcutaneous injections.
What is the current status of trial NCT07269210?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-12-08. Estimated completion is 2027-08.
What conditions does trial NCT07269210 study?
This clinical trial studies the following conditions: Severe Hypertriglyceridemia.
What interventions are being tested in trial NCT07269210?
The interventions under investigation include: Placebo (DRUG), Solbinsiran (DRUG).
Who is sponsoring clinical trial NCT07269210?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07269210 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Severe Hypertriglyceridemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07269210's enrollment target sits among peer trials
60 8th of 8 higher than 1 of 8 other Severe Hypertriglyceridemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Severe Hypertriglyceridemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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