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NCT07258849 · ClinicalTrials.gov registry record · Phase 1
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
A Phase 1 study of Healthy and Rheumatoid Arthritis (RA), sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 134
- Enrollment target
- 9
- Study locations
NCT07258849: Recruiting Phase 1 study of Healthy and Rheumatoid Arthritis (RA), sponsored by Eli Lilly and Company.
NCT07258849 is a Phase 1 study of Healthy and Rheumatoid Arthritis (RA) that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 134 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (79% lower). The trial reports 9 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07258849, a Phase 1 study of Healthy and Rheumatoid Arthritis (RA), is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 134 participants
- Enrollment target
- 9
- Study locations
Study Summary
The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA). The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. The study will last approximately 33 weeks excluding screening.
Primary Outcome
A summary of SAEs regardless of causality, will be reported in the Reported Adverse Events module
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY4213663
Study Locations (9)
Florida
- Clinical Research of West Florida, Inc. (Clearwater) - Clearwater
- GNP Research at Mark Jaffe, MD - Cooper City
- Fortrea Clinical Research Unit - Daytona Beach
- AGA Clinical Trials - Hialeah
- Advanced Pharma CR, LLC - Miami
- Floridian Clinical Research - Miami Lakes
Alabama
- Pinnacle Research Group, LLC - Anniston
Arizona
- Arizona Research Center - Phoenix
Nevada
- Oasis Clinical Research - Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2025-12-02 |
| Est. Completion | 2028-03 |
| Phase | Phase 1 |
What NCT07258849 shows while recruiting
NCT07258849 is an interventional study that assigns participants to a tested intervention. The registered 134 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (79% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07258849 lists 9 locations in 4 states (Florida, Alabama, Arizona).
Frequently Asked Questions
What is clinical trial NCT07258849 about?
NCT07258849 is a clinical study titled "A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis". The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA). The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the ...
What is the current status of trial NCT07258849?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 134 participants. The study started on 2025-12-02. Estimated completion is 2028-03.
What conditions does trial NCT07258849 study?
This clinical trial studies the following conditions: Healthy, Rheumatoid Arthritis (RA).
What interventions are being tested in trial NCT07258849?
The interventions under investigation include: Placebo (DRUG), LY4213663 (DRUG).
Who is sponsoring clinical trial NCT07258849?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07258849 being conducted?
This trial has 9 study locations across Alabama, Arizona, Florida, Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07258849's enrollment target sits among peer trials
134 170th of 1090 higher than 920 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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