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RECRUITING Phase 3

A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight

NCT07357415 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to investigate the efficacy and safety of different retatrutide dose escalation schemes in participants without type 2 diabetes who have obesity or overweight. Participation in the study will last about 113 weeks.

Conditions Studied

Interventions

  • DRUG Retatrutide

Study Locations (20)

Texas

  • Velocity Clinical Research, Dallas — Dallas
  • Cedar Health Research - Texas Native Health — Dallas
  • Cedar Health Research — Dallas
  • Cedar Health Research - Fort Worth — Fort Worth

California

  • Care Access - Huntington Beach — Huntington Beach
  • Los Angeles Institute for Metabolic Research — Los Angeles

Florida

  • New Horizon Research Center — Miami
  • Encore Medical Research - Weston — Weston

New York

  • NYC Research INC — Long Island City
  • Weill Cornell Medical College — New York

Arizona

  • Arizona Research Center — Phoenix

Hawaii

  • Pacific Diabetes & Endocrine Center — Honolulu

Kentucky

  • L-MARC Research Center — Louisville

Massachusetts

  • Brigham and Women's Hospital Diabetes Program — Boston

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 2026-01-24
Est. Completion 2028-11
Phase Phase 3

Sponsor

Eli Lilly and Company

704 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07357415

The ClinicalTrials.gov registry entry for NCT07357415 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention — of which Retatrutide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07357415 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Texas, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07357415 about?

NCT07357415 is a clinical study titled "A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight". The purpose of this study is to investigate the efficacy and safety of different retatrutide dose escalation schemes in participants without type 2 diabetes who have obesity or overweight. Participation in the study will last about 113 weeks.

What is the current status of trial NCT07357415?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 600 participants. The study started on 2026-01-24. Estimated completion is 2028-11.

What conditions does trial NCT07357415 study?

This clinical trial studies the following conditions: Obesity, Overweight. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07357415?

The interventions under investigation include: Retatrutide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07357415?

This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07357415 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Hawaii, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial