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NCT07218341 · ClinicalTrials.gov registry record · Phase 4
A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
A Phase 4 study, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 150
- Enrollment target
NCT07218341: Recruiting Phase 4 study, sponsored by Eli Lilly and Company.
NCT07218341 is a Phase 4 study that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 150 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07218341, a Phase 4 study, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 150 participants
- Enrollment target
Study Summary
This study will evaluate the long-term safety of pirtobrutinib in participants with previously treated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study is open to those who completed J2N-MC-JZNN/LOXO-BTK-20020 (NCT 04666038) for continued access to the study intervention or continued follow-up visits. Treatment will be given every 4 weeks and this study is expected to last about 5 years.
Interventions
- DRUG Pirtobrutinib
- DRUG Idelalisib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-03-09 |
| Est. Completion | 2032-12 |
| Phase | Phase 4 |
What NCT07218341 shows while recruiting
NCT07218341 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 2 interventions - of which Pirtobrutinib is the first listed.
NCT07218341 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07218341 about?
NCT07218341 is a clinical study titled "A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma". This study will evaluate the long-term safety of pirtobrutinib in participants with previously treated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study is open to those who completed J2N-MC-JZNN/LOXO-BTK-20020 (NCT 04666038) for continued access to the study interven...
What is the current status of trial NCT07218341?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 150 participants. The study started on 2026-03-09. Estimated completion is 2032-12.
What interventions are being tested in trial NCT07218341?
The interventions under investigation include: Pirtobrutinib (DRUG), Idelalisib (DRUG).
Who is sponsoring clinical trial NCT07218341?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07218341's enrollment target sits among peer trials
150 533rd of 2000 higher than 1,436 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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