Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07415044 · ClinicalTrials.gov registry record · Phase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
A Phase 2 study, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 1,431
- Enrollment target
NCT07415044: Recruiting Phase 2 study, sponsored by Eli Lilly and Company.
NCT07415044 is a Phase 2 study that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 1,431 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (976% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07415044, a Phase 2 study, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 1,431 participants
- Enrollment target
Study Summary
The main purpose of this study is to evaluate the safety and effectiveness of LY4268989 when compared to placebo in adult participants with moderately to severely active ulcerative colitis (UC). The study drug will be administered orally. The study will last up to approximately 108 weeks, excluding screening.
Interventions
- DRUG Placebo
- DRUG LY4268989
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,431 participants |
| Start Date | 2026-03-26 |
| Est. Completion | 2031-07 |
| Phase | Phase 2 |
What NCT07415044 shows while recruiting
NCT07415044 is an interventional study that assigns participants to a tested intervention. Its 1,431 participants enrollment target places it among the larger protocols in the corpus, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (976% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT07415044 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07415044 about?
NCT07415044 is a clinical study titled "LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis". The main purpose of this study is to evaluate the safety and effectiveness of LY4268989 when compared to placebo in adult participants with moderately to severely active ulcerative colitis (UC). The study drug will be administered orally. The study will last up to approximately 108 weeks, excluding...
What is the current status of trial NCT07415044?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 1,431 participants. The study started on 2026-03-26. Estimated completion is 2031-07.
What interventions are being tested in trial NCT07415044?
The interventions under investigation include: Placebo (DRUG), LY4268989 (DRUG).
Who is sponsoring clinical trial NCT07415044?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07415044's enrollment target sits among peer trials
1,431 12th of 2000 higher than 1,989 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04754022 · 1,440 participants · NA
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
- NCT04989790 · 1,440 participants · NA
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
- NCT06122246 · 1,440 participants · NA
PRESSURE CHECK: Find Your Path to Better Health
- NCT06324318 · 1,440 participants · Phase 2
Parenting in 2 Worlds Multisite Trial
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI