Boston Children's Hospital

462 total trials 110 currently recruiting 268 completed

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Trial Pipeline

462 total, page 2 of 10

RECRUITING NA

Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

NCT05464186

RECRUITING NA

Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot

NCT05236153

RECRUITING

Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome

NCT05528744

RECRUITING NA

The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults

NCT05258981

RECRUITING

Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery

NCT04299828

RECRUITING

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

NCT05354622

RECRUITING Phase 2

Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

NCT04380740

RECRUITING

Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease

NCT05241418

RECRUITING

VIGOR: Virtual Genome Center for Infant Health

NCT05205356

RECRUITING

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

NCT05071144

RECRUITING

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

NCT04439552

RECRUITING

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

NCT04770519

RECRUITING NA

Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis

NCT06701084

RECRUITING NA

Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

NCT04900597

RECRUITING NA

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

NCT04504227

RECRUITING

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

NCT04477460

RECRUITING Phase 1

Low Dose IL-2 for the Treatment of Crohn's Disease

NCT04263831

RECRUITING

Psychological Response and Readiness Associated With OCD of the Knee

NCT04649905

RECRUITING

Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

NCT04455906

RECRUITING

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

NCT04331639

RECRUITING

Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

NCT04604418

RECRUITING

Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis

NCT04103281

RECRUITING

Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis

NCT04103268

RECRUITING

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

NCT04712812

RECRUITING

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

NCT04629014

RECRUITING NA

Effects of Ketosis on Brain Function in Patients With T1DM

NCT04219709

RECRUITING NA

Very Low Carbohydrate Diets and Glucagon Response in T1DM

NCT04200391

RECRUITING NA

Type 1 Diabetes Management Using a Very Low Carbohydrate Versus Standard Diet

NCT03710928

RECRUITING

A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease

NCT04166526

RECRUITING NA

Optimizing Family Counseling for Anticipated Extremely Preterm Delivery

NCT03819933

RECRUITING

Application of a Systematic Developmental Assessment to a Novel Population: Infants With Rare Genetic Disorders

NCT03967743

RECRUITING

Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation

NCT03848923

RECRUITING Phase 4

The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

NCT03054831

RECRUITING Phase 4

Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present

NCT03655665

RECRUITING NA

Developing Fast Pediatric Imaging

NCT03761121

RECRUITING

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

NCT03593408

RECRUITING

Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency

NCT03758521

RECRUITING NA

A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB

NCT03530852

RECRUITING

Angelman Syndrome Natural History Study

NCT04507997

RECRUITING

Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation

NCT03532399

RECRUITING

Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

NCT03431064

RECRUITING NA

Transplantation of Autologously Derived Mitochondria Following Ischemia

NCT02851758

RECRUITING NA

Advanced Fetal Imaging - Phase II

NCT02840019

RECRUITING

Shwachman Diamond Syndrome Registry and Study

NCT06056908

RECRUITING

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

NCT02461446

RECRUITING

Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia

NCT02793999

RECRUITING

NIRS Monitoring in Premature Infants

NCT02601339

RECRUITING

Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections

NCT02271243

RECRUITING NA

Orchidopexy Randomized Clinical Assessment

NCT02235623

RECRUITING Phase 4

Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients

NCT02044497

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What the Pipeline for Boston Children's Hospital Shows

According to the ClinicalTrials.gov registry, Boston Children's Hospital is linked to 462 US clinical trials across every stage of research activity. Of those, 110 studies are currently recruiting, about 24% of the sponsor's indexed portfolio, and 268 are already marked complete, representing roughly 58% of the total.

The phase mix for Boston Children's Hospital reports 35 late-stage studies (Phase 3 and Phase 4 combined) and 53 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Boston Children's Hospital is Congenital Heart Disease with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.