Boston Children's Hospital
Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.
Trial Pipeline
462 total, page 2 of 10
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
NCT05464186
Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot
NCT05236153
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome
NCT05528744
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
NCT05258981
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
NCT04299828
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
NCT05354622
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
NCT04380740
Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease
NCT05241418
VIGOR: Virtual Genome Center for Infant Health
NCT05205356
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
NCT05071144
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
NCT04439552
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
NCT04770519
Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
NCT06701084
Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology
NCT04900597
Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
NCT04504227
Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event
NCT04477460
Low Dose IL-2 for the Treatment of Crohn's Disease
NCT04263831
Psychological Response and Readiness Associated With OCD of the Knee
NCT04649905
Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism
NCT04455906
High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy
NCT04331639
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
NCT04604418
Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis
NCT04103281
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
NCT04103268
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
NCT04712812
Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure
NCT04629014
Effects of Ketosis on Brain Function in Patients With T1DM
NCT04219709
Very Low Carbohydrate Diets and Glucagon Response in T1DM
NCT04200391
Type 1 Diabetes Management Using a Very Low Carbohydrate Versus Standard Diet
NCT03710928
A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
NCT04166526
Optimizing Family Counseling for Anticipated Extremely Preterm Delivery
NCT03819933
Application of a Systematic Developmental Assessment to a Novel Population: Infants With Rare Genetic Disorders
NCT03967743
Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation
NCT03848923
The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric
NCT03054831
Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present
NCT03655665
Developing Fast Pediatric Imaging
NCT03761121
Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support
NCT03593408
Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency
NCT03758521
A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB
NCT03530852
Angelman Syndrome Natural History Study
NCT04507997
Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation
NCT03532399
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
NCT03431064
Transplantation of Autologously Derived Mitochondria Following Ischemia
NCT02851758
Advanced Fetal Imaging - Phase II
NCT02840019
Shwachman Diamond Syndrome Registry and Study
NCT06056908
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
NCT02461446
Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia
NCT02793999
NIRS Monitoring in Premature Infants
NCT02601339
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
NCT02271243
Orchidopexy Randomized Clinical Assessment
NCT02235623
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients
NCT02044497
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 23 |
| Phase 3 | 12 |
| Phase 4 | 23 |
Therapeutic Areas
What the Pipeline for Boston Children's Hospital Shows
According to the ClinicalTrials.gov registry, Boston Children's Hospital is linked to 462 US clinical trials across every stage of research activity. Of those, 110 studies are currently recruiting, about 24% of the sponsor's indexed portfolio, and 268 are already marked complete, representing roughly 58% of the total.
The phase mix for Boston Children's Hospital reports 35 late-stage studies (Phase 3 and Phase 4 combined) and 53 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Boston Children's Hospital is Congenital Heart Disease with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.