Boston Children's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).
Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.
Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.
Top-decile sponsor footprint
Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
462 total, page 2 of 10
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
NCT05464186
Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot
NCT05236153
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome
NCT05528744
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
NCT05258981
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
NCT04299828
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
NCT05354622
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
NCT04380740
Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease
NCT05241418
VIGOR: Virtual Genome Center for Infant Health
NCT05205356
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
NCT05071144
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
NCT04439552
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
NCT04770519
Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
NCT06701084
Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology
NCT04900597
Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
NCT04504227
Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event
NCT04477460
Low Dose IL-2 for the Treatment of Crohn's Disease
NCT04263831
Psychological Response and Readiness Associated With OCD of the Knee
NCT04649905
Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism
NCT04455906
High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy
NCT04331639
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
NCT04604418
Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis
NCT04103281
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
NCT04103268
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
NCT04712812
Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure
NCT04629014
Effects of Ketosis on Brain Function in Patients With T1DM
NCT04219709
Very Low Carbohydrate Diets and Glucagon Response in T1DM
NCT04200391
Type 1 Diabetes Management Using a Very Low Carbohydrate Versus Standard Diet
NCT03710928
A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
NCT04166526
Optimizing Family Counseling for Anticipated Extremely Preterm Delivery
NCT03819933
Application of a Systematic Developmental Assessment to a Novel Population: Infants With Rare Genetic Disorders
NCT03967743
Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation
NCT03848923
The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric
NCT03054831
Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present
NCT03655665
Developing Fast Pediatric Imaging
NCT03761121
Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support
NCT03593408
Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency
NCT03758521
A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB
NCT03530852
Angelman Syndrome Natural History Study
NCT04507997
Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation
NCT03532399
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
NCT03431064
Transplantation of Autologously Derived Mitochondria Following Ischemia
NCT02851758
Advanced Fetal Imaging - Phase II
NCT02840019
Shwachman Diamond Syndrome Registry and Study
NCT06056908
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
NCT02461446
Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia
NCT02793999
NIRS Monitoring in Premature Infants
NCT02601339
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
NCT02271243
Orchidopexy Randomized Clinical Assessment
NCT02235623
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients
NCT02044497
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 23 |
| Phase 3 | 12 |
| Phase 4 | 23 |
Therapeutic Areas
What is open in the Boston Children's Hospital pipeline
110 recruiting of 462 indexed (24% open); 268 completed (58%).
Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).
Top condition: Congenital Heart Disease (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Boston Children's Hospital: open-pipeline peers nationwide
Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 462 trials (± recruiting share)
- University of Virginia · 449 trials · 22% recruiting
- Medical College of Wisconsin · 447 trials · 21% recruiting
- Alliance for Clinical Trials in Oncology · 446 trials · 7% recruiting
- Fred Hutchinson Cancer Center · 483 trials · 12% recruiting
Sponsors near 24% open enrollment (± trial volume)
- AdventHealth Translational Research Institute · 24% recruiting · 54 trials
- Auburn University · 24% recruiting · 54 trials
- Chugai Pharmaceutical · 24% recruiting · 17 trials
- HALEON · 24% recruiting · 34 trials
Related
What to do with this Boston Children's Hospital page
462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.
- 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.