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NCT02271243 · ClinicalTrials.gov registry record
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
A clinical trial, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 60
- Enrollment target
NCT02271243: Recruiting study, sponsored by Boston Children's Hospital.
NCT02271243 is a clinical trial that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 60 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02271243 is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 60 participants
- Enrollment target
Study Summary
Central line-associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with morbidity and mortality. This study will attempt to identify the source of bloodstream infections (BSIs) in children with CLABSI because we hypothesize that many of the BSIs that are currently classified as CLABSIs are actually laboratory-confirmed bloodstream infections (LCBI) that may be a result of mucosal barrier injury (MBI), also known as MBI-LCBI. In order to study this, we will isolate bacteria from multiple body sites of children that have BSI in order to compare these bacteria to the strain growing in their blood using whole-genome DNA sequencing. We will also evaluate biomarkers of MBI of the respiratory tract and GI tract.
Primary Outcome
Phylogeny will be determined using whole-genome DNA sequences of multiple bacterial colonies that grow from each body site.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2014-11 |
| Est. Completion | 2027-12 |
What NCT02271243 shows while recruiting
NCT02271243 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02271243 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02271243 about?
NCT02271243 is a clinical study titled "Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections". Central line-associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with morbidity and mortality. This study will attempt to identify the source of bloodstream infections (BSIs) in children with CLABSI because we hypothesize tha...
What is the current status of trial NCT02271243?
This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2014-11. Estimated completion is 2027-12.
Who is sponsoring clinical trial NCT02271243?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
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