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NCT02461446 · ClinicalTrials.gov registry record
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
A clinical trial of Autism and ASD, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 170
- Enrollment target
- 5
- Study locations
NCT02461446: Recruiting study of Autism and ASD, sponsored by Boston Children's Hospital.
NCT02461446 is a study of Autism and ASD that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 170 participants, roughly in line with the 182-participant average among 104 other Autism trials with a reported enrollment target. The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02461446, a study of Autism and ASD, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 170 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular biomarkers specific to PTEN ASD. In addition, this study will be creating and maintaining a biorepository and linked phenotypic database for PTEN ASD.
Primary Outcome
Verbal and non-verbal ability will be evaluated using Stanford Binet -5 or Mullen Scales of Early Learning (MSEL) at 12 months
Conditions Studied
Study Locations (5)
California
- University of California at Los Angeles - Los Angeles
- Stanford University Medical Center - Stanford
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
- Cleveland Clinic - Cleveland
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2015-05 |
| Est. Completion | 2026-12 |
What NCT02461446 shows while recruiting
NCT02461446 is an observational study that tracks outcomes without assigning an intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 182-participant average among 104 other Autism trials with a reported enrollment target.
The record links to 5 conditions, with Autism appearing as the primary indexed condition, and to 0 interventions.
NCT02461446 lists 5 locations in 3 states (California, Ohio, Massachusetts).
Frequently Asked Questions
What is clinical trial NCT02461446 about?
NCT02461446 is a clinical study titled "Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations". The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular biomarkers specific to PTEN ASD. In addition, this study will be creating and m...
What is the current status of trial NCT02461446?
This trial is currently recruiting. The enrollment target is 170 participants. The study started on 2015-05. Estimated completion is 2026-12.
What conditions does trial NCT02461446 study?
This clinical trial studies the following conditions: Autism, ASD, PTEN Hamartoma Tumor Syndrome, PTEN, Macrocephaly.
Who is sponsoring clinical trial NCT02461446?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02461446 being conducted?
This trial has 5 study locations across California, Massachusetts, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Autism
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02461446's enrollment target sits among peer trials
170 28th of 104 higher than 77 of 104 other Autism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Autism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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