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NCT04103281 · ClinicalTrials.gov registry record
Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis
A clinical trial of Sepsis, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT04103281: Recruiting study of Sepsis, sponsored by Boston Children's Hospital.
NCT04103281 is a study of Sepsis that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 75 participants, below the 6,564-participant average among 90 other Sepsis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04103281, a study of Sepsis, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in the lungs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood and secretions from the breathing tube of patients with sepsis so that they can work to develop therapies to prevent these cells from being harmful.
Primary Outcome
measure and report β2 integrin expression on neutrophils from blood and tracheal aspirate between sepsis patients and non-sepsis patients in pediatric population
Conditions Studied
Interventions
- OTHER Sepsis
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2020-09-01 |
| Est. Completion | 2026-12-31 |
What NCT04103281 shows while recruiting
NCT04103281 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 6,564-participant average among 90 other Sepsis trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Sepsis appearing as the primary indexed condition, and to 1 intervention - of which Sepsis is the first listed.
NCT04103281 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04103281 about?
NCT04103281 is a clinical study titled "Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis". In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that...
What is the current status of trial NCT04103281?
This trial is currently recruiting. The enrollment target is 75 participants. The study started on 2020-09-01. Estimated completion is 2026-12-31.
What conditions does trial NCT04103281 study?
This clinical trial studies the following conditions: Sepsis.
What interventions are being tested in trial NCT04103281?
The interventions under investigation include: Sepsis (OTHER).
Who is sponsoring clinical trial NCT04103281?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04103281 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04103281's enrollment target sits among peer trials
75 62nd of 90 higher than 29 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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