Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 3 of 10

RECRUITING

MRI Assessment of Placental Health

NCT02297724

RECRUITING

Lymphatic Anomalies Registry for the Assessment of Outcome Data

NCT02399527

RECRUITING

Genetics of Epilepsy and Related Disorders

NCT01858285

RECRUITING

Gene Discovery Core, The Manton Center

NCT02743845

RECRUITING

Preterm Lung Patient Registry

NCT00951366

RECRUITING

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

NCT00499317

RECRUITING

Identifying Genetic Causes of IC/BPS

NCT00389142

RECRUITING

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

NCT03059420

RECRUITING

Molecular and Genetic Studies of Congenital Myopathies

NCT00272883

RECRUITING

Molecular Analysis of Patients With Neuromuscular Disease

NCT00390104

ACTIVE NOT RECRUITING NA

Digital Otoscopy Versus Standard Otoscopy on the Diagnosis and Treatment of Otitis Media in Young Children

NCT07328555

ACTIVE NOT RECRUITING NA

Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children

NCT06731660

ACTIVE NOT RECRUITING

Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

NCT05687292

ACTIVE NOT RECRUITING

Neutrophil Phenotypic Profiling and Surgical Site Infections in Surgical Patients

NCT04773457

ACTIVE NOT RECRUITING NA

Developmental Intervention for Hospitalized Newborns With Congenital Heart Disease

NCT05885113

ACTIVE NOT RECRUITING NA

Overcoming Barriers to Accessing Genetic Medicine

NCT05064241

ACTIVE NOT RECRUITING NA

Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

NCT05405426

ACTIVE NOT RECRUITING NA

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966

ACTIVE NOT RECRUITING Phase 3

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

NCT05600426

ACTIVE NOT RECRUITING NA

Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome

NCT05638412

ACTIVE NOT RECRUITING NA

Readiness Outcomes Affecting Return to Sport 2.0: An Intervention Feasibility & Pilot Study

NCT05338385

ACTIVE NOT RECRUITING NA

Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain

NCT04488757

ACTIVE NOT RECRUITING Phase 4

Investigating Dupilumab's Effect in Asthma by Genotype

NCT03694158

ACTIVE NOT RECRUITING

Improving Infant Hydrocephalus Outcomes in Uganda

NCT03650101

ACTIVE NOT RECRUITING NA

Predicting Pediatric Pulmonary Vein Stenosis Outcomes Using Data Acquired During a Cardiac Catheterization

NCT04696289

ACTIVE NOT RECRUITING Phase 2

Preventing Asthma in High Risk Kids

NCT02570984

ACTIVE NOT RECRUITING

Airway Management of Pediatric Patients With Klippel-Feil Syndrome

NCT03741790

ACTIVE NOT RECRUITING

Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion

NCT02860091

ACTIVE NOT RECRUITING Phase 3

Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score

NCT03386539

ACTIVE NOT RECRUITING

Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury

NCT03263325

ACTIVE NOT RECRUITING

Pediatric ACL: Understanding Treatment Options

NCT02772770

ACTIVE NOT RECRUITING

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

NCT02461420

ACTIVE NOT RECRUITING

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

NCT02461459

ACTIVE NOT RECRUITING

Mathematical Modeling to Predict the Duration of Thrombocytopenia in Neonates

NCT02802982

ACTIVE NOT RECRUITING

Multi-Center Adolescent Clavicle Fracture Trial: Operative vs. Non-Operative Treatment

NCT04250415

ACTIVE NOT RECRUITING

The Women's Health Study: From Adolescence to Adulthood

NCT01738204

ACTIVE NOT RECRUITING Phase 2

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

NCT01659606

ACTIVE NOT RECRUITING

Phenotypic and Genetic Factors in Autism Spectrum Disorders

NCT00910559

ACTIVE NOT RECRUITING

Genetic Contributions to Autism Spectrum Disorders

NCT01160783

NOT YET RECRUITING Phase 4

Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients

NCT06397781

NOT YET RECRUITING NA

Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP

NCT06804382

NOT YET RECRUITING

Creating Linked Inpatient CGM for Kids

NCT06899503

NOT YET RECRUITING Phase 4

EEG Biomarkers for ADHD Stimulant Treatment

NCT07650643

NOT YET RECRUITING Phase 2

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

NCT07218575

NOT YET RECRUITING

Validation of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) for Adolescents

NCT07532109

NOT YET RECRUITING

Continuous Wireless Ultrasound to Monitor Fetal Health

NCT07676474

NOT YET RECRUITING NA

MY01 Pressure Monitoring in Adolescent Tibia Fractures

NCT07674043

NOT YET RECRUITING NA

Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth

NCT07545005

NOT YET RECRUITING NA

Readiness Outcomes Affecting Return to Sport 3.0

NCT07476430

NOT YET RECRUITING Phase 3

Gabapentin and Oxcarbazepine for Chronic Neuropathic Pain in Children and Adolescents: A Clinical Effectiveness Study

NCT02219373

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Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Boston Children's Hospital pipeline card: 462 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.