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NCT05258981 · ClinicalTrials.gov registry record · NA

The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults

A NA study of Congenital Heart Disease, sponsored by Boston Children's Hospital.

Recruiting
Registry status
NA
Development phase
225
Enrollment target
1
Study location

NCT05258981: Recruiting NA study of Congenital Heart Disease, sponsored by Boston Children's Hospital.

NCT05258981 is a NA study of Congenital Heart Disease that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 225 participants, below the 470-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05258981, a NA study of Congenital Heart Disease, is actively recruiting participants, sponsored by Boston Children's Hospital.

RECRUITING
Registry status
NA
Development phase
225 participants
Enrollment target
1
Study location

Study Summary

The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST MRI

Study Locations (1)

Massachusetts

  • Boston Children's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 225 participants
Start Date 2022-07-01
Est. Completion 2026-06
Phase NA
Boston Children's Hospital

462 total trials

What NCT05258981 shows while recruiting

NCT05258981 is an interventional study that assigns participants to a tested intervention. The registered 225 participants enrollment target is mid-sized for trials with a published cap, below the 470-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (52% lower).

The record links to 1 condition, with Congenital Heart Disease appearing as the primary indexed condition, and to 1 intervention - of which MRI is the first listed.

NCT05258981 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05258981 about?

NCT05258981 is a clinical study titled "The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults". The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).

What is the current status of trial NCT05258981?

This trial is currently recruiting. It is a NA study. The enrollment target is 225 participants. The study started on 2022-07-01. Estimated completion is 2026-06.

What conditions does trial NCT05258981 study?

This clinical trial studies the following conditions: Congenital Heart Disease.

What interventions are being tested in trial NCT05258981?

The interventions under investigation include: MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05258981?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05258981 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Congenital Heart Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05258981's enrollment target sits among peer trials

225 15th of 63 higher than 49 of 63 other Congenital Heart Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Congenital Heart Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05258981, the US trial registry maintained by the National Library of Medicine. NCT05258981 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.