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Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
NCT04504227 · View on ClinicalTrials.gov ↗
Study Summary
This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Thin liquid swallows
- DIETARY_SUPPLEMENT Slightly thickened liquid swallows
- DIETARY_SUPPLEMENT Mildly thickened liquid swallows
- DIETARY_SUPPLEMENT Moderately thickened liquid swallows
Study Locations (1)
Massachusetts
- Boston Children's Hospital — Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04504227
The ClinicalTrials.gov registry entry for NCT04504227 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston Children's Hospital, which has 752 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Dysphagia appearing as the primary indexed condition, and to 4 interventions — of which Thin liquid swallows is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04504227 reports 1 study location spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04504227 about?
NCT04504227 is a clinical study titled "Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia". This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.
What is the current status of trial NCT04504227?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2021-04-01. Estimated completion is 2026-08-31.
What conditions does trial NCT04504227 study?
This clinical trial studies the following conditions: Dysphagia, Aspiration, Brief Resolved Unexplained Event (BRUE), Apparent Life Threatening Event (ALTE). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04504227?
The interventions under investigation include: Thin liquid swallows (DIETARY_SUPPLEMENT), Slightly thickened liquid swallows (DIETARY_SUPPLEMENT), Mildly thickened liquid swallows (DIETARY_SUPPLEMENT), Moderately thickened liquid swallows (DIETARY_SUPPLEMENT). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04504227?
This trial is sponsored by Boston Children's Hospital, which has 752 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04504227 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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