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NCT04504227 · ClinicalTrials.gov registry record · NA
Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
A NA study of Dysphagia and Aspiration, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT04504227: Recruiting NA study of Dysphagia and Aspiration, sponsored by Boston Children's Hospital.
NCT04504227 is a NA study of Dysphagia and Aspiration that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 200 participants, above the 166-participant average among 35 other Dysphagia trials with a reported enrollment target (20% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04504227, a NA study of Dysphagia and Aspiration, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.
Primary Outcome
We will calculate swallow risk index (SRI) from impedance-manometry results to compare mean SRI with thin liquids and thickened liquids for subjects with aspiration compared to mean SRI for thin liquids and thickened liquids in subjects without aspiration.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Thin liquid swallows
- DIETARY_SUPPLEMENT Slightly thickened liquid swallows
- DIETARY_SUPPLEMENT Mildly thickened liquid swallows
- DIETARY_SUPPLEMENT Moderately thickened liquid swallows
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What NCT04504227 shows while recruiting
NCT04504227 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 166-participant average among 35 other Dysphagia trials with a reported enrollment target (20% higher).
The record links to 4 conditions, with Dysphagia appearing as the primary indexed condition, and to 4 interventions - of which Thin liquid swallows is the first listed.
NCT04504227 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04504227 about?
NCT04504227 is a clinical study titled "Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia". This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.
What is the current status of trial NCT04504227?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2021-04-01. Estimated completion is 2026-08-31.
What conditions does trial NCT04504227 study?
This clinical trial studies the following conditions: Dysphagia, Aspiration, Brief Resolved Unexplained Event (BRUE), Apparent Life Threatening Event (ALTE).
What interventions are being tested in trial NCT04504227?
The interventions under investigation include: Thin liquid swallows (DIETARY_SUPPLEMENT), Slightly thickened liquid swallows (DIETARY_SUPPLEMENT), Mildly thickened liquid swallows (DIETARY_SUPPLEMENT), Moderately thickened liquid swallows (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04504227?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04504227 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dysphagia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04504227's enrollment target sits among peer trials
200 10th of 35 higher than 26 of 35 other Dysphagia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dysphagia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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