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Endometriosis: full-pipeline trial registry
26 of 49 indexed Endometriosis trials are currently recruiting.
Corpus placement: #281 of 28,707 conditions by registered trial count.
49 US clinical trials · 26 currently recruiting · #281 of 28,707 conditions by registered trial count
Endometriosis: 49 US clinical trials tracked, 26 recruiting.
Endometriosis is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 26 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 5 of these trials.
Enrollment posture brief
Registry condition endometriosis
OPEN 26 | RECR 53% | LATE 13 | EARLY 12 | RANK #281 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Pain, Chronic (53% recruiting · 49 trials)
Endometriosis lists 26 open slots (53% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Endometriosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Endometriosis is recruiting above its size-band peers.
26 of 49 indexed trials (53.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Endometriosis trials is spread across many organizations.
Boston Children's Hospital accounts for 5 of 49 trials (10.2%). 34 distinct sponsors appear on at least one study for this condition label.
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Typical Endometriosis enrolment sits around 100 participants.
Median target enrolment is 100 among the 49 trials that report a genuine target (sentinel values excluded). 24 of those (49%) plan for fewer than 100 participants.
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Endometriosis research is mostly interventional.
39 interventional and 10 observational studies make up this index (79.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
49 total, page 1 of 1
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
Aspira Women's Health
NCT05245695
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Sumitomo Pharma Switzerland
NCT05862272
Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp
Yale University
NCT06375811
Histologic Comparison of Ablative Techniques for Endometriosis
TriHealth
NCT06414083
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
Johns Hopkins University
NCT06847685
Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain
University of Michigan
NCT07100782
Endometriosis Pain
Washington University School of Medicine
NCT06101303
Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
Mayo Clinic
NCT04567771
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
Samphire Group
NCT06974773
Nutritional Intervention for Endometriosis
Physicians Committee for Responsible Medicine
NCT05175248
Endometriosis and Migraine
Washington University School of Medicine
NCT06785129
The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
Main Line Health
NCT06439524
Thromboxane Function in Women With Endometriosis
Penn State University
NCT05962034
Proof of Concept Study to Eval MetriDx Lab-developed Test to Identify Endometriosis-specific Bio Markers
Hera Biotech
NCT05698212
Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)
Medtronic - MITG
NCT07120945
Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain
Washington University School of Medicine
NCT06549985
Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis
Baylor College of Medicine
NCT06577233
Cardiovascular Disease Risk in Women With Endometriosis
Yale University
NCT03746535
The Impact of Yoga on Endometriosis-Related Pain
Milton S. Hershey Medical Center
NCT06559852
Physical Therapy After Endometriosis Excision
Oregon Health and Science University
NCT07127783
Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
Mclean Hospital
NCT06477406
Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
Penn State University
NCT05059626
Endometriosis and Microvascular Dysfunction: Role of Inflammation
Penn State University
NCT05069740
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
University of North Carolina, Chapel Hill
NCT05480995
Feasibility of a Mindfulness Intervention for Endometriosis Surgery
Milton S. Hershey Medical Center
NCT06141720
Glycemic Regulation as Endometriosis Adjunct Treatment
Boston Children's Hospital
NCT06611501
The Women's Health Study: From Adolescence to Adulthood
Boston Children's Hospital
NCT01738204
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain
AbbVie
NCT04333576
The EMPOWER Study: Endometriosis Diagnosis Using MicroRNA
Dot Laboratories
NCT04598698
Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance
Johns Hopkins University
NCT03756480
An AHEI Dietary Intervention to Reduce Pain in Women With Endometriosis
Fred Hutchinson Cancer Center
NCT04259788
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
University of Louisville
NCT04554693
Global Study of Women's Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00849173
Characteristics of Patient Population With Endometriosis
St. Louis University
NCT03002870
SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain
Myovant Sciences
NCT03654274
Medical Treatment of Endometriosis-Associated Pelvic Pain
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00229996
A Comparison of Narrow Band Imaging (NBI) and Standard White Light Laparoscopy to Detect Endometriosis
Mercy Medical Center
NCT01464775
A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain
Hope Medicine (Nanjing) Co.
NCT05101317
Cabergoline for the Treatment of Chronic Pain Due to Endometriosis
Boston Children's Hospital
NCT03928288
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
University of Texas Southwestern Medical Center
NCT01793584
Effects of Endometriosis on Bone Mineral Density
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00291278
Endometriosis Trial: Study of NBI-56418 in Endometriosis
Abbott
NCT00109512
Novel Web-based, Self-directed Intervention for Chronic Pelvic Pain
University of Michigan
NCT06352840
Supplementation in Adolescent Girls With Endometriosis
Boston Children's Hospital
NCT02387931
The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial
Boston Children's Hospital
NCT00474851
Endometriosis : Traditional Medicine vs Hormone Therapy
National Center for Complementary and Integrative Health (NCCIH)
NCT00034047
Microbiome and Immunologic Analysis - Women With Endometriosis
Mayo Clinic
NCT04159740
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
Colorado Center for Reproductive Medicine
NCT00621179
BGS649 Monotherapy in Moderate to Severe Endometriosis Patients
Mereo BioPharma
NCT01190475
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 9 |
| Phase 3 | 7 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Endometriosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Endometriosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Endometriosis page
49 registered trials, 26 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 26 Endometriosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Boston Children's Hospital sponsors the most Endometriosis trials on record, review their full trial history before evaluating a specific study. See Boston Children's Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Endometriosis condition card totals 49 registered trials; most-linked intervention Placebo; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.