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2026 data Public-data reference. official source

Endometriosis

Open-data reference.

49 US clinical trials · 26 currently recruiting

Active & Recent Trials

RECRUITING 1,200 participants

Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)

Aspira Women's Health

NCT05245695

RECRUITING Phase 3 1,000 participants

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Sumitomo Pharma Switzerland

NCT05862272

RECRUITING Phase 3 297 participants

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Yale University

NCT06375811

RECRUITING NA 141 participants

Histologic Comparison of Ablative Techniques for Endometriosis

TriHealth

NCT06414083

RECRUITING 140 participants

Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

Johns Hopkins University

NCT06847685

RECRUITING Phase 3 130 participants

Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain

University of Michigan

NCT07100782

RECRUITING 120 participants

Endometriosis Pain

Washington University School of Medicine

NCT06101303

RECRUITING NA 120 participants

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

Mayo Clinic

NCT04567771

RECRUITING NA 120 participants

Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

Samphire Group

NCT06974773

RECRUITING NA 120 participants

Nutritional Intervention for Endometriosis

Physicians Committee for Responsible Medicine

NCT05175248

RECRUITING 120 participants

Endometriosis and Migraine

Washington University School of Medicine

NCT06785129

RECRUITING Phase 3 110 participants

The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial

Main Line Health

NCT06439524

RECRUITING Phase 4 96 participants

Thromboxane Function in Women With Endometriosis

Penn State University

NCT05962034

RECRUITING Phase 2 75 participants

Proof of Concept Study to Eval MetriDx Lab-developed Test to Identify Endometriosis-specific Bio Markers

Hera Biotech

NCT05698212

RECRUITING NA 70 participants

Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)

Medtronic - MITG

NCT07120945

RECRUITING NA 60 participants

Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain

Washington University School of Medicine

NCT06549985

RECRUITING Phase 4 60 participants

Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis

Baylor College of Medicine

NCT06577233

RECRUITING Early Phase 1 40 participants

Cardiovascular Disease Risk in Women With Endometriosis

Yale University

NCT03746535

RECRUITING NA 30 participants

The Impact of Yoga on Endometriosis-Related Pain

Milton S. Hershey Medical Center

NCT06559852

RECRUITING NA 30 participants

Physical Therapy After Endometriosis Excision

Oregon Health and Science University

NCT07127783

RECRUITING Phase 2 30 participants

Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis

Mclean Hospital

NCT06477406

RECRUITING Phase 4 28 participants

Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee

Penn State University

NCT05059626

RECRUITING Early Phase 1 24 participants

Endometriosis and Microvascular Dysfunction: Role of Inflammation

Penn State University

NCT05069740

RECRUITING Phase 2 24 participants

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

University of North Carolina, Chapel Hill

NCT05480995

RECRUITING NA 20 participants

Feasibility of a Mindfulness Intervention for Endometriosis Surgery

Milton S. Hershey Medical Center

NCT06141720

RECRUITING Phase 2 14 participants

Glycemic Regulation as Endometriosis Adjunct Treatment

Boston Children's Hospital

NCT06611501

ACTIVE NOT RECRUITING 2,000 participants

The Women's Health Study: From Adolescence to Adulthood

Boston Children's Hospital

NCT01738204

ACTIVE NOT RECRUITING Phase 3 800 participants

Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

AbbVie

NCT04333576

ACTIVE NOT RECRUITING 750 participants

The EMPOWER Study: Endometriosis Diagnosis Using MicroRNA

Dot Laboratories

NCT04598698

ACTIVE NOT RECRUITING 135 participants

Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance

Johns Hopkins University

NCT03756480

ACTIVE NOT RECRUITING NA 109 participants

An AHEI Dietary Intervention to Reduce Pain in Women With Endometriosis

Fred Hutchinson Cancer Center

NCT04259788

ACTIVE NOT RECRUITING Phase 4 90 participants

The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery

University of Louisville

NCT04554693

COMPLETED 1,459 participants

Global Study of Women's Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00849173

COMPLETED NA 1,100 participants

Characteristics of Patient Population With Endometriosis

St. Louis University

NCT03002870

COMPLETED Phase 3 802 participants

SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain

Myovant Sciences

NCT03654274

COMPLETED Phase 3 194 participants

Medical Treatment of Endometriosis-Associated Pelvic Pain

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00229996

COMPLETED NA 167 participants

A Comparison of Narrow Band Imaging (NBI) and Standard White Light Laparoscopy to Detect Endometriosis

Mercy Medical Center

NCT01464775

COMPLETED Phase 2 142 participants

A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain

Hope Medicine (Nanjing) Co.

NCT05101317

COMPLETED Phase 2 129 participants

Cabergoline for the Treatment of Chronic Pain Due to Endometriosis

Boston Children's Hospital

NCT03928288

COMPLETED NA 100 participants

Surgical Success After Laparoscopic vs Abdominal Hysterectomy

University of Texas Southwestern Medical Center

NCT01793584

COMPLETED 80 participants

Effects of Endometriosis on Bone Mineral Density

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00291278

COMPLETED Phase 2 76 participants

Endometriosis Trial: Study of NBI-56418 in Endometriosis

Abbott

NCT00109512

COMPLETED NA 70 participants

Novel Web-based, Self-directed Intervention for Chronic Pelvic Pain

University of Michigan

NCT06352840

COMPLETED Phase 4 69 participants

Supplementation in Adolescent Girls With Endometriosis

Boston Children's Hospital

NCT02387931

COMPLETED Phase 2 53 participants

The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial

Boston Children's Hospital

NCT00474851

COMPLETED Phase 1 50 participants

Endometriosis : Traditional Medicine vs Hormone Therapy

National Center for Complementary and Integrative Health (NCCIH)

NCT00034047

COMPLETED 48 participants

Microbiome and Immunologic Analysis - Women With Endometriosis

Mayo Clinic

NCT04159740

COMPLETED Phase 4 37 participants

Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF

Colorado Center for Reproductive Medicine

NCT00621179

COMPLETED Phase 2 6 participants

BGS649 Monotherapy in Moderate to Severe Endometriosis Patients

Mereo BioPharma

NCT01190475

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 9
Phase 3 7
Phase 4 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Endometriosis Trial Landscape

ClinicalTrials.gov lists 49 US studies indexed under Endometriosis, and 26 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Endometriosis shows 13 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Endometriosis is led by Boston Children's Hospital with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Endometriosis?

PlainTrial tracks 49 US clinical trials for Endometriosis, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Endometriosis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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