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NCT04770519 · ClinicalTrials.gov registry record
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
A clinical trial of Strabismus and Nystagmus, Congenital, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT04770519: Recruiting study of Strabismus and Nystagmus, Congenital, sponsored by Boston Children's Hospital.
NCT04770519 is a study of Strabismus and Nystagmus, Congenital that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 400 participants, below the 687-participant average among 9 other Strabismus trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04770519, a study of Strabismus and Nystagmus, Congenital, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esotropia and their parents and siblings, and (3) individuals with infantile nystagmus and their parents. Whole exome and/or whole genome sequencing will be used to identify genetic variants shared by family members with strabismus and to identify genetic causes of nystagmus.
Primary Outcome
genetic variants shared by family members with strabismus
Conditions Studied
Interventions
- GENETIC whole genome sequencing or whole exome sequencing
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2021-09-03 |
| Est. Completion | 2030-12 |
What NCT04770519 shows while recruiting
NCT04770519 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 687-participant average among 9 other Strabismus trials with a reported enrollment target (42% lower).
The record links to 2 conditions, with Strabismus appearing as the primary indexed condition, and to 1 intervention - of which whole genome sequencing or whole exome sequencing is the first listed.
NCT04770519 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04770519 about?
NCT04770519 is a clinical study titled "Genetic Studies of Strabismus, Nystagmus, and Associated Disorders". Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esot...
What is the current status of trial NCT04770519?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2021-09-03. Estimated completion is 2030-12.
What conditions does trial NCT04770519 study?
This clinical trial studies the following conditions: Strabismus, Nystagmus, Congenital.
What interventions are being tested in trial NCT04770519?
The interventions under investigation include: whole genome sequencing or whole exome sequencing (GENETIC).
Who is sponsoring clinical trial NCT04770519?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04770519 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04770519's enrollment target sits among peer trials
400 3rd of 9 higher than 7 of 9 other Strabismus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Strabismus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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