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NCT04770519 · ClinicalTrials.gov registry record

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

A clinical trial of Strabismus and Nystagmus, Congenital, sponsored by Boston Children's Hospital.

Recruiting
Registry status
400
Enrollment target
1
Study location

NCT04770519 is a study of Strabismus and Nystagmus, Congenital that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 400 participants, below the 687-participant average among 9 other Strabismus trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04770519, a study of Strabismus and Nystagmus, Congenital, is actively recruiting participants, sponsored by Boston Children's Hospital.

RECRUITING
Registry status
400 participants
Enrollment target
1
Study location

Study Summary

Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esotropia and their parents and siblings, and (3) individuals with infantile nystagmus and their parents. Whole exome and/or whole genome sequencing will be used to identify genetic variants shared by family members with strabismus and to identify genetic causes of nystagmus.

Interventions

  • GENETIC whole genome sequencing or whole exome sequencing

Study Locations (1)

Massachusetts

  • Boston Children's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2021-09-03
Est. Completion 2030-12

Sponsor

Boston Children's Hospital

462 total trials

What the Registry Record Tells You About NCT04770519

The ClinicalTrials.gov registry entry for NCT04770519 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 687-participant average among 9 other Strabismus trials with a reported enrollment target (42% lower). The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Strabismus appearing as the primary indexed condition, and to 1 intervention - of which whole genome sequencing or whole exome sequencing is the first listed.

NCT04770519 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04770519 about?

NCT04770519 is a clinical study titled "Genetic Studies of Strabismus, Nystagmus, and Associated Disorders". Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esot...

What is the current status of trial NCT04770519?

This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2021-09-03. Estimated completion is 2030-12.

What conditions does trial NCT04770519 study?

This clinical trial studies the following conditions: Strabismus, Nystagmus, Congenital.

What interventions are being tested in trial NCT04770519?

The interventions under investigation include: whole genome sequencing or whole exome sequencing (GENETIC).

Who is sponsoring clinical trial NCT04770519?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04770519 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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