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NCT04712812 · ClinicalTrials.gov registry record
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
A clinical trial of Hereditary Spastic Paraplegia and SPG50, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 700
- Enrollment target
- 1
- Study location
NCT04712812 is a study of Hereditary Spastic Paraplegia and SPG50 that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 700 participants, above the 116-participant average among 5 other Hereditary Spastic Paraplegia trials with a reported enrollment target (503% higher). The trial reports 1 study location across 1 state.
The verdict
NCT04712812, a study of Hereditary Spastic Paraplegia and SPG50, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 700 participants
- Enrollment target
- 1
- Study location
Study Summary
The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or saliva) from male and female patients, under the age of 30, who exhibited early onset symptoms of HSP with (1) a clinical diagnosis of hereditary spastic paraplegia and (2) the presence of variants in HSP related genes and/or be a relative of a person with such a diagnosis. Currently, the treatment for this disorder is generally symptomatic and available therapies improve quality of life, but are grossly inefficient in slowing the disease progression. Access to the registry information will be limited to the study staff who are responsible for recruitment and maintenance of the registry. We hope that recruitment into the registry for studies will advance knowledge of the causes, clinical course, diagnosis, and treatment of these conditions.
Conditions Studied
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 700 participants |
| Start Date | 2020-04-27 |
| Est. Completion | 2030-12-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04712812
The ClinicalTrials.gov registry entry for NCT04712812 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 700 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 116-participant average among 5 other Hereditary Spastic Paraplegia trials with a reported enrollment target (503% higher). The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.
The record links to 10 conditions, with Hereditary Spastic Paraplegia appearing as the primary indexed condition, and to 0 interventions.
NCT04712812 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04712812 about?
NCT04712812 is a clinical study titled "Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia". The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or saliva) from male and female patients, under the age of 30, who exhibited early onset symptoms of HSP ...
What is the current status of trial NCT04712812?
This trial is currently recruiting. The enrollment target is 700 participants. The study started on 2020-04-27. Estimated completion is 2030-12-31.
What conditions does trial NCT04712812 study?
This clinical trial studies the following conditions: Hereditary Spastic Paraplegia, SPG50, Early Onset Hereditary Spastic Paraplegia, SPG4, SPG47.
Who is sponsoring clinical trial NCT04712812?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04712812 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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