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NCT04299828 · ClinicalTrials.gov registry record
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
A clinical trial of Congenital Heart Disease and Coagulation, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT04299828 is a study of Congenital Heart Disease and Coagulation that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 100 participants, below the 472-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04299828, a study of Congenital Heart Disease and Coagulation, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this proposal is to prospectively collect data from a series of 200 patients (all ages) undergoing complex cardiac surgical procedures involving cardiopulmonary bypass (CPB) to: 1. Measure the number of blood activated circulating monocytes before, during and after cardiac surgery and serum GABA and pro-inflammatory cytokine levels 2. Understand the correlation between GABA and inflammatory cytokines (and/or activated monocytes) and 3. Assess the correlation between thrombosis and monocyte activation in patients undergoing cardiac surgery under CPB and at risk of thrombosis.
Conditions Studied
Interventions
- OTHER Discarded blood samples
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-05-31 |
| Est. Completion | 2026-12 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04299828
The ClinicalTrials.gov registry entry for NCT04299828 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 472-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (79% lower). The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Congenital Heart Disease appearing as the primary indexed condition, and to 1 intervention - of which Discarded blood samples is the first listed.
NCT04299828 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04299828 about?
NCT04299828 is a clinical study titled "Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery". The goal of this proposal is to prospectively collect data from a series of 200 patients (all ages) undergoing complex cardiac surgical procedures involving cardiopulmonary bypass (CPB) to: 1. Measure the number of blood activated circulating monocytes before, during and after cardiac surgery and s...
What is the current status of trial NCT04299828?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2022-05-31. Estimated completion is 2026-12.
What conditions does trial NCT04299828 study?
This clinical trial studies the following conditions: Congenital Heart Disease, Coagulation.
What interventions are being tested in trial NCT04299828?
The interventions under investigation include: Discarded blood samples (OTHER).
Who is sponsoring clinical trial NCT04299828?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04299828 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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