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ClinicalTrials.gov 4 recruiting now full pipeline small index

Otitis Media: full-pipeline trial registry

4 of 16 indexed Otitis Media trials are currently recruiting.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 4 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Otitis Media: 16 US clinical trials tracked, 4 recruiting.

Otitis Media is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 3 of these trials.

Enrollment posture brief

Registry condition otitis-media

OPEN 4 | RECR 25% | LATE 3 | EARLY 3 | RANK #1060 | SPON 3

Nearest open-share peer: Abdominal Cancer (25% recruiting · 8 trials)

Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Otitis Media (this)25%Allergy18.8%
Open-enrollment share among volume-matched conditions near Otitis Media

Otitis Media lists 4 open slots (25% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Otitis Media on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Otitis Media is recruiting below its size-band peers.

    4 of 16 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Otitis Media research.

    Boston Children's Hospital accounts for 3 of 16 trials (18.8%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Otitis Media enrolment sits around 165 participants.

    Median target enrolment is 165 among the 15 trials that report a genuine target (sentinel values excluded). 6 of those (40%) plan for fewer than 100 participants.

  4. Otitis Media research is mostly interventional.

    13 interventional and 3 observational studies make up this index (81.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 23Phase 31Phase 42

Open and recent trials

16 total, page 1 of 1

RECRUITING NA 235 participants

Coherent Optical Detection of Middle Ear Disease

Medical College of Wisconsin

NCT05353569

RECRUITING 200 participants

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

Smith & Nephew

NCT05915078

RECRUITING Phase 4 125 participants

Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present

Boston Children's Hospital

NCT03655665

RECRUITING NA 66 participants

In-Office Clinical Study of the Solo+ TTD

AventaMed DAC

NCT05741333

ACTIVE NOT RECRUITING 165 participants

Diagnostic Utility of Otosight Middle Ear Scope

Baylor College of Medicine

NCT05641285

ACTIVE NOT RECRUITING NA 40 participants

Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children

Boston Children's Hospital

NCT06731660

COMPLETED Phase 3 55,779 participants

Improving Otitis Media Care With Clinical Decision Support

Children's Hospital of Philadelphia

NCT00581711

COMPLETED 3,000 participants

ParentLink: Better and Safer Emergency Care for Children

Boston Children's Hospital

NCT00457600

COMPLETED NA 400 participants

Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00365092

COMPLETED NA 310 participants

The Impact of Ear Pain Anticipatory Guidance Counseling on Otitis Related Visits in a Low Income Population

University of Colorado, Denver

NCT02616458

COMPLETED NA 258 participants

In-Office Study of the Hummingbird® in Children 6 Months-21 Years Old

Preceptis Medical

NCT03544138

COMPLETED Phase 4 99 participants

A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in Children

Deborah Gentile

NCT00189462

COMPLETED NA 70 participants

Tympanostomy Tube Placement in Children in the Office (Inova Study)

Integra LifeSciences Corporation

NCT01496287

COMPLETED Phase 2 38 participants

Study of FAECC Scale (Modified FLACC) to Evaluate Ear Pain in Children With Acute Otitis Media

Arbor Pharmaceuticals

NCT01588535

COMPLETED Phase 2 25 participants

Effect of Simethicone on Eustachian Tube Dysfunction

University of Pittsburgh

NCT01312038

COMPLETED Phase 2

Nervous System Manipulation and Botanicals for the Treatment of Recurrent Ear Infections in Children

National Center for Complementary and Integrative Health (NCCIH)

NCT00010465

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 1
Phase 4 2

Named interventions

Most-linked intervention names on Otitis Media records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
2 trials
Botanicals Drug
1 trials
Craniosacral Osteopathic Manipulative Treatment Procedure
1 trials
Tube Delivery System (TDS) Device
1 trials
Insertion of tympanostomy tubes Procedure
1 trials
Hummingbird Tympanostomy Tube System (H-TTS) Device
1 trials
patient-driven health IT product Procedure
1 trials
benzocaine Drug
1 trials

US sites by state

Facility locations filed on Otitis Media trials. A trial with sites in several states counts in each.

Pennsylvania 5 trials
Massachusetts 3 trials
Kentucky 3 trials
Florida 3 trials
Utah 2 trials
Texas 2 trials
North Dakota 2 trials
California 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Otitis Media page

16 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Otitis Media condition card totals 16 registered trials; most-linked intervention Placebo; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.