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ClinicalTrials.gov 4 recruiting now official registry

Otitis Media clinical trials

Every US clinical trial registered for Otitis Media — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

16 US clinical trials · 4 currently recruiting

The research picture

Otitis Media has 16 registered US clinical trials, 4 of them open to new participants right now — about 25% of the total.

4
recruiting participants now
25%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
3
top sponsor: Boston Children's Hospital

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 235 participants

Coherent Optical Detection of Middle Ear Disease

Medical College of Wisconsin

NCT05353569

RECRUITING 200 participants

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

Smith & Nephew

NCT05915078

RECRUITING Phase 4 125 participants

Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present

Boston Children's Hospital

NCT03655665

RECRUITING NA 66 participants

In-Office Clinical Study of the Solo+ TTD

AventaMed DAC

NCT05741333

ACTIVE NOT RECRUITING 165 participants

Diagnostic Utility of Otosight Middle Ear Scope

Baylor College of Medicine

NCT05641285

ACTIVE NOT RECRUITING NA 40 participants

Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children

Boston Children's Hospital

NCT06731660

COMPLETED Phase 3 55,779 participants

Improving Otitis Media Care With Clinical Decision Support

Children's Hospital of Philadelphia

NCT00581711

COMPLETED 3,000 participants

ParentLink: Better and Safer Emergency Care for Children

Boston Children's Hospital

NCT00457600

COMPLETED NA 400 participants

Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00365092

COMPLETED NA 310 participants

The Impact of Ear Pain Anticipatory Guidance Counseling on Otitis Related Visits in a Low Income Population

University of Colorado, Denver

NCT02616458

COMPLETED NA 258 participants

In-Office Study of the Hummingbird® in Children 6 Months-21 Years Old

Preceptis Medical

NCT03544138

COMPLETED Phase 4 99 participants

A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in Children

Deborah Gentile

NCT00189462

COMPLETED NA 70 participants

Tympanostomy Tube Placement in Children in the Office (Inova Study)

Integra LifeSciences Corporation

NCT01496287

COMPLETED Phase 2 38 participants

Study of FAECC Scale (Modified FLACC) to Evaluate Ear Pain in Children With Acute Otitis Media

Arbor Pharmaceuticals

NCT01588535

COMPLETED Phase 2 25 participants

Effect of Simethicone on Eustachian Tube Dysfunction

University of Pittsburgh

NCT01312038

COMPLETED Phase 2

Nervous System Manipulation and Botanicals for the Treatment of Recurrent Ear Infections in Children

National Center for Complementary and Integrative Health (NCCIH)

NCT00010465

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Otitis Media Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Otitis Media, and 4 of those are currently open to recruitment — roughly 25% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Otitis Media shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Otitis Media is led by Boston Children's Hospital with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Otitis Media?

PlainTrial tracks 16 US clinical trials for Otitis Media, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Otitis Media?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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