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ClinicalTrials.gov 112 recruiting now early-phase tilt #41 of 28,707 conditions

Autism Spectrum Disorder: early-phase trial registry

112 of 225 indexed Autism Spectrum Disorder trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #41 of 28,707 conditions by registered trial count.

225 US clinical trials · 112 currently recruiting · #41 of 28,707 conditions by registered trial count

Autism Spectrum Disorder: 225 US clinical trials tracked, 112 recruiting.

Autism Spectrum Disorder is the subject of 225 registered US clinical trials on ClinicalTrials.gov, 112 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 49 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 19 of these trials.

Enrollment posture brief

Registry condition autism-spectrum-disorder

OPEN 112 | RECR 50% | LATE 4 | EARLY 49 | RANK #41 | SPON 19

Nearest open-share peer: Alzheimer Disease (50% recruiting · 312 trials)

Autism Spectrum Disorder (th…50%Mild Cognitive Impairment48.5%Sickle Cell Disease44.4%Coronary Artery Disease25.9%Diabetes Mellitus23.3%
Open-enrollment share among volume-matched conditions near Autism Spectrum Disorder

Autism Spectrum Disorder lists 112 open slots (50% of 225 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Autism Spectrum Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Autism Spectrum Disorder is recruiting above its size-band peers.

    112 of 225 indexed trials (49.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Autism Spectrum Disorder trials is spread across many organizations.

    Stanford University accounts for 19 of 225 trials (8.4%). 113 distinct sponsors appear on at least one study for this condition label.

  3. Most Autism Spectrum Disorder trials plan to enrol fewer than 100 people.

    Median target enrolment is 67 among the 225 trials that report a genuine target (sentinel values excluded). 147 of those (65.3%) plan for fewer than 100 participants.

  4. Autism Spectrum Disorder research is mostly interventional.

    195 interventional and 30 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 237Phase 32Phase 42

Open and recent trials

225 total, page 1 of 5

RECRUITING 1,500 participants

International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder

Stalicla

NCT05590715

RECRUITING 1,100 participants

Developing Brain, Impulsivity and Compulsivity

National Institute of Mental Health (NIMH)

NCT04631042

RECRUITING 1,000 participants

Longitudinal Study of Neurogenetic Disorders

Columbia University

NCT03492060

RECRUITING 1,000 participants

Patterns of Neurodevelopmental Disorders

Richard Frye

NCT06213090

RECRUITING NA 720 participants

Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool

Vanderbilt University Medical Center

NCT05047224

RECRUITING NA 672 participants

Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services

San Diego State University

NCT06651086

RECRUITING NA 540 participants

Improving Social Communication in Individuals With ASD Using AI

Stanford University

NCT05987774

RECRUITING Phase 4 500 participants

AWARE: Management of ADHD in Autism Spectrum Disorder

Daniel Coury

NCT05916339

RECRUITING Phase 3 500 participants

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

Intra-Cellular Therapies

NCT06229210

RECRUITING 500 participants

Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

Southwest Autism Research & Resource Center

NCT04322734

RECRUITING NA 470 participants

Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults

University of Pittsburgh

NCT06158581

RECRUITING NA 440 participants

Improving the Part C Early Intervention Service Delivery System for Children with ASD

University of Washington

NCT05114538

RECRUITING NA 376 participants

Physical Activity and Community EmPOWERment Project

University of North Carolina, Chapel Hill

NCT06740162

RECRUITING NA 350 participants

School-based Paraeducator Education for Engagement at Recess

University of Washington

NCT06559267

RECRUITING 350 participants

SenseToKnow Autism Screening Device Validation Study

Duke University

NCT05874466

RECRUITING NA 300 participants

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

University of North Carolina, Chapel Hill

NCT06060860

RECRUITING NA 300 participants

Early Diagnostic Response Model (EDRM)

Emory University

NCT05419895

RECRUITING NA 297 participants

COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD

Ball State University

NCT06309160

RECRUITING NA 280 participants

Autism Research Project With Non-Invasive Near-Infrared Light Stimulation

University of Texas at Austin

NCT06203938

RECRUITING NA 240 participants

Evaluating Additive Effects of Including Canines in Regulating Together

Children's Hospital Medical Center, Cincinnati

NCT05803343

RECRUITING NA 224 participants

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Center, Cincinnati

NCT06705907

RECRUITING NA 200 participants

A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

University of Colorado, Denver

NCT05863520

RECRUITING NA 200 participants

Cerebellar Stimulation and Cognitive Control

Krystal Parker, PhD

NCT03217110

RECRUITING Phase 4 196 participants

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Gagan Joshi

NCT06853665

RECRUITING NA 192 participants

STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade

Children's Hospital Medical Center, Cincinnati

NCT06552286

RECRUITING NA 188 participants

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05176808

RECRUITING Phase 2 184 participants

Optimizing Outcomes for Young Autistic Children

Northwestern University

NCT05926687

RECRUITING NA 180 participants

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

University of Missouri-Columbia

NCT04545606

RECRUITING NA 180 participants

Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders

Children's Hospital Medical Center, Cincinnati

NCT06227780

RECRUITING NA 160 participants

Iterative Redesign of a Multifaceted Implementation Strategy for a School-based Behavioral Skills Intervention (RUBI)

University of Washington

NCT06508515

RECRUITING NA 150 participants

Family, Responsibility, Education, Support, and Health for Families With a Child With Autism

University of California, San Diego

NCT05741840

RECRUITING Phase 2 144 participants

Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial

Stanford University

NCT05664789

RECRUITING NA 139 participants

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

Baylor College of Medicine

NCT06537128

RECRUITING NA 132 participants

Peer Interventions for Preschoolers With Autism

University of Kansas

NCT05799599

RECRUITING NA 120 participants

Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

Stanford University

NCT04899544

RECRUITING NA 106 participants

Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

National Institute of Mental Health (NIMH)

NCT04798274

RECRUITING NA 104 participants

How Simplified Language Affects Comprehension and Learning in Young Autistic Children

Michigan State University

NCT05707923

RECRUITING 100 participants

Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder

Loma Linda University

NCT06059352

RECRUITING Phase 1 100 participants

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park

NCT07304440

RECRUITING Phase 3 100 participants

Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances

Vanda Pharmaceuticals

NCT05361707

RECRUITING NA 100 participants

Family-Implemented Treatment on the Behavioral Inflexibility of Children With Autism

University of Kansas

NCT05125003

RECRUITING Phase 2 100 participants

Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)

Montefiore Medical Center

NCT03202303

RECRUITING NA 100 participants

Word Learning From Parentese in Autistic Children

The University of Texas at Dallas

NCT06649916

RECRUITING Phase 2 96 participants

Oxytocin Effects on Bone in Children With Autism Spectrum Disorder

Elizabeth Austen Lawson

NCT05754073

RECRUITING Phase 2 90 participants

Telehealth-Enabled Versus In-Person Parent-Mediated Behavioral Treatment for Challenging Behaviors in Children With ASD

Stanford University

NCT05268796

RECRUITING NA 90 participants

Neural Basis of Social Cognition Deficits

Loma Linda University

NCT05185128

RECRUITING NA 80 participants

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

American University

NCT05396352

RECRUITING Phase 2 80 participants

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

Southwest Autism Research & Resource Center

NCT04060017

RECRUITING NA 80 participants

STEPS Implementation Trial

University of Alabama, Tuscaloo

NCT05695885

RECRUITING 80 participants

SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism

American Federation of Medical Synergetics

NCT03222375

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 37
Phase 3 2
Phase 4 2

Named interventions

Most-linked intervention names on Autism Spectrum Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
18 trials
Placebo Other
4 trials
Propranolol Drug
3 trials
SENSE Theatre Behavioral
2 trials
Program for the Education and Enrichment of Relational Skills Behavioral
2 trials
Surviving and Thriving in the Real World Behavioral
2 trials
JASPER Behavioral
2 trials
Cognilum TM: Light Treatment Condition Device
2 trials

US sites by state

Facility locations filed on Autism Spectrum Disorder trials. A trial with sites in several states counts in each.

California 54 trials
New York 30 trials
Ohio 23 trials
Pennsylvania 19 trials
Massachusetts 19 trials
Arizona 17 trials
Texas 16 trials
Maryland 15 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Autism Spectrum Disorder page

225 registered trials, 112 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 112 Autism Spectrum Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Stanford University sponsors the most Autism Spectrum Disorder trials on record, review their full trial history before evaluating a specific study. See Stanford University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Autism Spectrum Disorder condition card totals 225 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.