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NCT07176273 · ClinicalTrials.gov registry record · NA

Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

A NA study of Post Traumatic Stress Disorder and PTSD, sponsored by The University of Texas Health Science Center at San Antonio.

Recruiting
Registry status
NA
Development phase
302
Enrollment target
4
Study locations

NCT07176273: Recruiting NA study of Post Traumatic Stress Disorder and PTSD, sponsored by The University of Texas Health Science Center at San Antonio.

NCT07176273 is a NA study of Post Traumatic Stress Disorder and PTSD that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 302 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (54% lower). The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07176273, a NA study of Post Traumatic Stress Disorder and PTSD, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.

RECRUITING
Registry status
NA
Development phase
302 participants
Enrollment target
4
Study locations

Study Summary

By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly that might improve treatment response. The investigators also want to learn how best to match the right type and amount of treatment to each individual veteran. By conducting this research project, they hope to: * See if trying a different treatment strategy for veterans not responding to their first PTSD treatment would be more helpful * See if sending text message prompts between sessions encourages more completion of between-session homework

Primary Outcome

The PCL-5 is a psychometrically valid measure and commonly used assessment of PTSD symptoms. A total score is calculated by adding up the ratings for each of the 20 items, which range from 0 to 4 (0=Not at all, 4=Extremely). Higher scores reflect more severe symptoms. A score below 31 generally suggests a sub-clinical range, while scores of 31 or above fall within the clinical range, indicating probable PTSD.

Interventions

  • BEHAVIORAL Modular Cognitive Processing Therapy
  • BEHAVIORAL Modular Prolonged Exposure Therapy
  • BEHAVIORAL Step Down Treatment
  • BEHAVIORAL Digital Interventions
  • BEHAVIORAL Cognitive Processing Therapy (CPT)

Study Locations (4)

Michigan

  • Ann Arbor VA - Ann Arbor
  • Battle Creek VA - Battle Creek

Georgia

  • Augusta VA - Augusta

Utah

  • Salt Lake City VA - Salt Lake City

Trial Details

FieldValue
Enrollment Target 302 participants
Start Date 2025-12-12
Est. Completion 2028-08-14
Phase NA

What NCT07176273 shows while recruiting

NCT07176273 is an interventional study that assigns participants to a tested intervention. The registered 302 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (54% lower).

The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 5 interventions - of which Modular Cognitive Processing Therapy is the first listed.

NCT07176273 reports a single indexed study location in Michigan, Georgia, Utah.

Frequently Asked Questions

What is clinical trial NCT07176273 about?

NCT07176273 is a clinical study titled "Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)". By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly that might improve treatment response. The investigators also want to le...

What is the current status of trial NCT07176273?

This trial is currently recruiting. It is a NA study. The enrollment target is 302 participants. The study started on 2025-12-12. Estimated completion is 2028-08-14.

What conditions does trial NCT07176273 study?

This clinical trial studies the following conditions: Post Traumatic Stress Disorder, PTSD.

What interventions are being tested in trial NCT07176273?

The interventions under investigation include: Modular Cognitive Processing Therapy (BEHAVIORAL), Modular Prolonged Exposure Therapy (BEHAVIORAL), Step Down Treatment (BEHAVIORAL), Digital Interventions (BEHAVIORAL), Cognitive Processing Therapy (CPT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT07176273?

This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07176273 being conducted?

This trial has 4 study locations across Georgia, Michigan, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07176273's enrollment target sits among peer trials

302 26th of 262 higher than 236 of 262 other Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07176273, the US trial registry maintained by the National Library of Medicine. NCT07176273 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.