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NCT05310097 · ClinicalTrials.gov registry record · NA
Cognitive Processing Therapy (CPT) Memory Support (MS) Study
A NA study of PTSD, sponsored by Boston University.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05310097 is a NA study of PTSD that is actively recruiting participants, run by Boston University. The registered enrollment target is 100 participants, below the 301-participant average among 154 other PTSD trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05310097, a NA study of PTSD, is actively recruiting participants, sponsored by Boston University.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The efficacy of psychological interventions for posttraumatic stress disorder (PTSD) is likely limited by the difficulty participants have learning and remembering important therapy content. Accordingly, the present study will examine the utility of integrating a Memory Support (MS) intervention into Cognitive Processing Therapy (CPT), an empirically supported and widely disseminated treatment for PTSD. MS was designed to integrate techniques aimed at facilitating encoding, consolidation, and retrieval of new learning into existing treatments, and has been shown to improve outcomes when integrated into cognitive therapy for depression. A pilot randomized controlled trial (n=52) comparing CPT with Memory Support (CPT+MS) to CPT-alone will be conducted. Study participants will be adults diagnosed with PTSD. The primary aim of the trial will be to determine if CPT+MS will lead to greater memory and learning of therapy content relative to CPT-alone, and to establish the acceptability and feasibility of integrating MS into CPT. Secondary aims include a preliminary examination of treatment efficacy, as indicated by the magnitude of changes in PTSD symptoms between conditions, and target validation, as indicated by associations between memory and learning of therapy content and treatment response. Exploratory analyses will examine several indicators of baseline memory-related cognitive functioning as predictors of memory and learning of therapy content, providing preliminary data to inform future research on personalized application of MS. Results of the trial will advance scientific knowledge about methods for optimizing memory and learning as a mechanism for improving PTSD treatment outcomes.
Conditions Studied
Interventions
- BEHAVIORAL CPT
- BEHAVIORAL MS
Study Locations (1)
Massachusetts
- VA Boston Healthcare System - Jamaica Plain
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-01-04 |
| Est. Completion | 2027-04 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05310097
The ClinicalTrials.gov registry entry for NCT05310097 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 301-participant average among 154 other PTSD trials with a reported enrollment target (67% lower). The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with PTSD appearing as the primary indexed condition, and to 2 interventions - of which CPT is the first listed.
NCT05310097 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05310097 about?
NCT05310097 is a clinical study titled "Cognitive Processing Therapy (CPT) Memory Support (MS) Study". The efficacy of psychological interventions for posttraumatic stress disorder (PTSD) is likely limited by the difficulty participants have learning and remembering important therapy content. Accordingly, the present study will examine the utility of integrating a Memory Support (MS) intervention int...
What is the current status of trial NCT05310097?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-01-04. Estimated completion is 2027-04.
What conditions does trial NCT05310097 study?
This clinical trial studies the following conditions: PTSD.
What interventions are being tested in trial NCT05310097?
The interventions under investigation include: CPT (BEHAVIORAL), MS (BEHAVIORAL).
Who is sponsoring clinical trial NCT05310097?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05310097 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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