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NCT05700279 · ClinicalTrials.gov registry record · NA
Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset
A NA study of Chronic Pain and PTSD, sponsored by Rush University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 345
- Enrollment target
- 1
- Study location
NCT05700279: Recruiting NA study of Chronic Pain and PTSD, sponsored by Rush University Medical Center.
NCT05700279 is a NA study of Chronic Pain and PTSD that is actively recruiting participants, run by Rush University Medical Center. The registered enrollment target is 345 participants, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05700279, a NA study of Chronic Pain and PTSD, is actively recruiting participants, sponsored by Rush University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 345 participants
- Enrollment target
- 1
- Study location
Study Summary
Although most people recover from acute pain (such as pain caused by injury, surgery, repetitive motion, or unknown causes), many people do not fully recover and will experience chronic pain. Untreated posttraumatic stress disorder (PTSD) appears to be a key risk factor for the transition from acute pain to chronic pain. However, few published studies have addressed the issue of preventing the transition from acute to chronic pain via PTSD reduction. This project will aim to test whether trauma-related PTSD symptoms can be reduced using either Stellate Ganglion Block (SGB) treatment or Cognitive Processing Therapy (CPT), and whether reducing PTSD symptoms can prevent the transition from non-injury based acute pain to chronic pain.
Primary Outcome
Intensity of chronic pain reported by subject. The PROMIS Pain Intensity scale consists of 3 questions with a 5-point response scale ranging from "Had no pain" -to "Very severe. " Participants are asked how intense their pain has been in the past 7 days. Higher scores indicate more intense pain.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Processing Therapy
- PROCEDURE Stellate Ganglion Block
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 345 participants |
| Start Date | 2023-09-01 |
| Est. Completion | 2027-02-01 |
| Phase | NA |
What NCT05700279 shows while recruiting
NCT05700279 is an interventional study that assigns participants to a tested intervention. The registered 345 participants enrollment target is mid-sized for trials with a published cap, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (55% lower).
The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Cognitive Processing Therapy is the first listed.
NCT05700279 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05700279 about?
NCT05700279 is a clinical study titled "Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset". Although most people recover from acute pain (such as pain caused by injury, surgery, repetitive motion, or unknown causes), many people do not fully recover and will experience chronic pain. Untreated posttraumatic stress disorder (PTSD) appears to be a key risk factor for the transition from acute...
What is the current status of trial NCT05700279?
This trial is currently recruiting. It is a NA study. The enrollment target is 345 participants. The study started on 2023-09-01. Estimated completion is 2027-02-01.
What conditions does trial NCT05700279 study?
This clinical trial studies the following conditions: Chronic Pain, PTSD.
What interventions are being tested in trial NCT05700279?
The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL), Stellate Ganglion Block (PROCEDURE).
Who is sponsoring clinical trial NCT05700279?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05700279 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05700279's enrollment target sits among peer trials
345 42nd of 301 higher than 260 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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