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NCT05120635 · ClinicalTrials.gov registry record · NA
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
A NA study of PTSD and Fear, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT05120635 is a NA study of PTSD and Fear that is actively recruiting participants, run by Duke University. The registered enrollment target is 80 participants, below the 301-participant average among 154 other PTSD trials with a reported enrollment target (73% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT05120635, a NA study of PTSD and Fear, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments. The purpose of this study is to understand the brain mechanisms that produce fear and anxiety in humans. To accomplish this goal, we will measure the brain activity along with the heart rate and skin perspiration of patients while they are completing tasks on a computer. Some of the tasks will also use a virtual reality headset and transport the patient in a video game-like environment. These tasks will expose the participants to various levels of fear-provoking images. Participants with responsive neurostimulation (RNS) implants will be enrolled under Pro00117931 at Duke, but their results for fear and anxiety tasks will be reported under NCT05120635.
Conditions Studied
Interventions
- DEVICE Deep Brain Stimulation
- BEHAVIORAL Virtual and augmented reality tasks
Study Locations (2)
California
- University of California Los Angeles - Los Angeles
North Carolina
- Duke University Health System - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2021-10-01 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05120635
The ClinicalTrials.gov registry entry for NCT05120635 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 301-participant average among 154 other PTSD trials with a reported enrollment target (73% lower). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with PTSD appearing as the primary indexed condition, and to 2 interventions - of which Deep Brain Stimulation is the first listed.
NCT05120635 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, North Carolina.
Frequently Asked Questions
What is clinical trial NCT05120635 about?
NCT05120635 is a clinical study titled "Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans". Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments. The purpose of this study is to understand the brain mechanisms that produce...
What is the current status of trial NCT05120635?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2021-10-01. Estimated completion is 2026-06-30.
What conditions does trial NCT05120635 study?
This clinical trial studies the following conditions: PTSD, Fear, GAD, Emotional Memory.
What interventions are being tested in trial NCT05120635?
The interventions under investigation include: Deep Brain Stimulation (DEVICE), Virtual and augmented reality tasks (BEHAVIORAL).
Who is sponsoring clinical trial NCT05120635?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05120635 being conducted?
This trial has 2 study locations across California, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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